Publications by authors named "Jose Ramos"

Introduction: Carotid endarterectomy (CEA) remains the gold standard intervention for stroke prevention in patients with carotid artery stenosis but the surgical technique continues evolving with research being conducted on minimally invasive alternatives. Mini-skin incision CEA has emerged as a more aesthetically appealing and less painful alternative to the traditional technique with a potential impact on main procedural events. We aimed to provide a review of the literature and to compare the mini-skin incision with the traditional approach.

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Because plants are immobile, they have developed intricate mechanisms to sense and absorb nutrients, adjusting their growth and development accordingly. Sulfur is an essential macroelement, but our understanding of its metabolism and homeostasis is limited. LSU (RESPONSE TO LOW SULFUR) proteins are plant-specific proteins with unknown molecular functions and were first identified during transcriptomic studies on sulfur deficiency in Arabidopsis.

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Varicella-zoster virus infections have increased globally, with complications such as postherpetic neuralgia and neurological sequelae. The recombinant vaccine against herpes zoster is proposed as a preventive strategy. This systematic review evaluates its effectiveness and safety in healthy and high-risk populations.

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  • Maternal deaths in low and middle-income countries, like Brazil, are often due to hypertensive issues, with preeclampsia being a major cause.
  • Key factors contributing to these deaths include poor identification of high-risk women, inadequate prevention measures, and delays in diagnosis and treatment.
  • To address this, the "4 P Rule" is suggested, emphasizing Adequate Prevention, Vigilant Prenatal Care, Timely Delivery, and Safe Postpartum to improve management and reduce mortality rates from preeclampsia.
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The non-conventional yeast Kluyveromyces marxianus has recently emerged as a promising candidate for many food, environment, and biotechnology applications. This yeast is thermotolerant and has robust growth under many adverse conditions. Here, we show that its ability to grow under potassium-limiting conditions is much better than that of Saccharomyces cerevisiae, suggesting a very efficient and high-affinity potassium uptake system(s) in this species.

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We describe the geographical variation in tree species composition across Amazonian forests and show how environmental conditions are associated with species turnover. Our analyses are based on 2023 forest inventory plots (1 ha) that provide abundance data for a total of 5188 tree species. Within-plot species composition reflected both local environmental conditions (especially soil nutrients and hydrology) and geographical regions.

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Plasma levels of endocannabinoids (eCBs) are very dynamic and variable in different circumstances and pathologies. The aim of the study was to determine the levels of the main eCBs and N-acylethanolamines (NAEs) in COVID-19 patients during the acute and post-acute phase of SARS-CoV-2 infection. Samples collected before December 31, 2020 were used for the determination of circulating eCB levels by liquid chromatography-tandem mass spectrometry (LC-MS/MS).

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Mental disorders account for a large and increasing health burden worldwide. Characterizing the spectrum of mental disorders and trends over time in adolescents should influence education policies and support preventative strategies at schools. Retrospective study of all hospitalizations in Spain in adolescents 11-18-years old, including mental disorders as diagnosis using the Spanish National Registry of Hospital Discharges.

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  • The study aimed to understand stillbirth ratios and investigate the causes of fetal mortality by analyzing medical records from multiple obstetric care centers over a nine-year period.
  • A total of 3,390 stillbirth cases were reviewed, showing a decrease in the stillbirth ratio from 10.74 to 9.31 per 1,000 live births, with common causes being intrauterine hypoxia and unspecified reasons.
  • The study highlights a need for standardized investigation practices for stillbirths since many cases lacked comprehensive testing, especially for unspecified causes of death.
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  • The yeast Debaryomyces hansenii is important for food and biotechnology but is challenging to study genetically.
  • Researchers have used advanced imaging techniques and fluorescent dyes to analyze its sub-cellular structures, including mitochondria and the cell wall, revealing its biological processes for the first time.
  • This innovative approach not only enhances the understanding of D. hansenii but also provides a framework for studying other difficult-to-manipulate biological systems.
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  • Several clinical trials confirm that dupilumab is effective and safe for treating atopic dermatitis (AD), but there’s limited information on its long-term real-world outcomes.
  • A retrospective study of 312 adult patients in Portugal found a 30-month drug survival rate of 82%, with 12.5% discontinuing treatment mainly due to treatment failure or adverse effects.
  • Significant improvements were observed in skin severity (EASI score), itchiness (NRS), and quality of life (DLQI), showcasing the drug's effectiveness over the follow-up period.
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Background And Aims: The prevalence and mortality of chronic liver disease has risen significantly. In end stage liver disease (ESLD) the survival of patients is approximately 2 years. Despite the poor prognosis and high symptom burden of these patients, integration of palliative care is reduced.

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The European "Green Deal" policies are shifting toward more sustainable and environmentally conscious agricultural practices, reducing the use of chemical fertilizer and pesticides. This implies exploring alternative strategies. One promising alternative to improve plant nutrition and reinforce plant defenses is the use of beneficial microorganisms in the rhizosphere, such as "Plant-growth-promoting rhizobacteria and fungi".

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  • - The study focused on Generalized Pustular Psoriasis (GPP), a rare and serious skin condition, examining its course, treatment approaches, and how often patients used healthcare services in Portugal from 2002 to 2023.
  • - It assessed 59 adult patients, revealing that most had a history of another psoriasis type and faced significant health issues, with 64% requiring hospitalization and many experiencing severe symptoms such as fever and high white blood cell counts.
  • - Despite treatment, 98% of patients had at least one flare-up, and only a small number showed improvement by the study's end, indicating a need for better understanding and new treatment options to alleviate the disease's impact.
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Machine learning (ML) methods are increasingly being applied to analyze biological signals. For example, ML methods have been successfully applied to the human electroencephalogram (EEG) to classify neural signals as pathological or non-pathological and to predict working memory performance in healthy and psychiatric patients. ML approaches can quickly process large volumes of data to reveal patterns that may be missed by humans.

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Background And Aims: Carvedilol has emerged as the preferred β-blocker for treating portal hypertension. However, there is still a debate in dosing regimen, with a potential lower bioavailability in once-daily regimens. The aim of this study is to assess the acute effects of carvedilol posology in patients with clinically significant portal hypertension (CSPH), as a surrogate marker of bioavailability.

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  • Amazonia's floodplain system is the largest and most biodiverse, but our understanding of its forest species and their unique roles is still limited, especially as changing flood patterns impact these communities.
  • About one-sixth of the tree diversity in Amazonia is specifically adapted to live in floodplain environments, indicating a significant ecological specialization within these forests.
  • The study emphasizes that the unique composition of floodplain forests is influenced by regional flooding patterns, highlighting the necessity of maintaining overall hydrological health to ensure the survival of Amazon's tree diversity and its essential ecosystem functions.
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Chagas disease (CD) is a typical tropical illness caused by . The objective of this study was to assess the prevalence of Chagas disease in communities in two states of the Brazilian Amazon. Data collection occurred in July in the Alto Juruá region of Acre and in December in the communities of Humaitá, Amazonas, in 2019.

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