Frameless radiosurgery for intraocular metastatic tumor: Case report.

Aim: The aim of this case report is to describe the technique and response using frameless radiosurgery technique in intraocular metastases.

Background: Intraocular metastases are the most common malignant lesion within the eye and its prevalence is probably underestimated. This is of great interest for oncologist as there are new treatment options with high rates of tumor control maintaining patient's quality of life.

Rapid desensitization to chemotherapy drugs in oncologic patients. A good and safe option. A two-case presentation.

Hypersensitivity reactions, and anaphylactic or anaphylactoid reactions to oncologic chemotherapy drugs, such as platinum, taxanes, monoclonal antibodies and others, limit their therapeutic use due to the fear of the treating physician to induce severe or deadly reactions in patients who have presented previous reactions to the same. This leads to the use of less effective or second line chemotherapy schemes for the sensitivity of the tumor. The rapid desensitization to such medications in patients who have presented previous reactions is a safe and proven effective procedure, which allows the use of the most effective chemotherapy drugs for the tumor sensitivity in oncologic patients even if they have presented hypersensitivity reactions to those drugs previously.