Efficacy of in-vivo counting in parathyroid radioguided surgery and usefulness of its association with scintigraphy and intraoperative PTHi.

Aim: To evaluate the efficacy of the γ probe, alone and in combination with other techniques, in primary hyperparathyroidism surgery, as well as its ability to distinguish between single-gland and multiple-gland diseases.

Materials And Methods: Sixty-three patients with primary hyperparathyroidism submitted to radioguided parathyroidectomy, with a minimum follow-up of 1 year, were included. A preoperatory scintigraphy with technetium-99m methoxyisobutylisonitrile was performed in all cases and the excised specimens were histopathologically examined.

Radioguided surgery of primary hyperparathyroidism in a population with a high prevalence of thyroid pathology.

Purpose: Patients with concomitant thyroid pathology are usually excluded from minimally invasive radioguided parathyroidectomy (MIRP). We assessed the value in these patients of the gamma probe, alone or in combination with other techniques, in MIRP and unilateral or bilateral approaches. We evaluated its performance in association with intraoperative determination of intact parathyroid hormone (ioPTHi) and preoperative (99m)Tc-MIBI dual phase scintigraphy.