Hypersensitivity pneumonitis: application of a new diagnostic algorithm to a time series of the disease.

Background: The diagnostic criteria for Hypersensitivity pneumonitis (HP) have changed over time. Our aim is to apply a recent diagnostic algorithm to a historical series of patients diagnosed with HP to assess its distribution according to current diagnostic criteria and the diagnostic confidence achieved.

Research Design And Methods: Application to each patient the algorithm criteria.

Sarcoidosis. Disease progression based on radiological and functional course: Predictive factors.

Background: Sarcoidosis is a multiorgan granulomatous disease with a variable course.

Oobjectives: The purpose of this study is to identify the patients that are more likely to experience disease progression.

Methods: A retrospective study in patients ≥18 years.

Immunohistochemical evaluation of EGFR expression in lip squamous cell carcinoma. Correlation with clinicopathological characteristics.

Background: The majority of lip cancer is the squamous cell carcinoma (SCC) type that exhibits clinical and biological characteristics intermediate between skin and oral SCC. The aim of this study was to assess the impact of epidermal growth factor receptor (EGFR) expression on prognosis of lip squamous cell carcinoma (LSCC) and to relate it with clinicopathological features. The role of EGFR expression as a possible therapeutic target was also discussed.

Vaginal involvement in a woman with Darier's disease: a case report.

Background: Involvement of the female genital tract by Darier's disease, an unusual genodermatosis, is uncommon, and the manifestation of the disease in a cervicovaginal smear is exceptionally rare.

Case: A 39-year-old woman had an abnormal Pap smear caused by involvement of the female genital tract by Darier's disease. Cytologic examination showed features consistent with a low grade squamous intraepithelial lesion, but during a biopsy it was found to be vaginal involvement by Darier's disease.