Publications by authors named "Jose R Castro Conde"

Purpose: To assess the clinical effectiveness of treating acute seizures with midazolam and lidocaine infusion.

Methods: This single-center historical cohort study included 39 term neonates with electrographic seizures who underwent treatment with midazolam (1st line) and lidocaine (2nd line). Therapeutic response was measured using continuous video-EEG monitoring.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the correlation between immature EEG patterns and neurodevelopment in small-gestational-age (SGA) full-term infants, comparing them to appropriate-gestational-age (AGA) infants.
  • - 50 SGA and 44 AGA neonates underwent continuous video-EEG monitoring, with subsequent assessments of their motor, cognitive, and language development at 2 years old using the Bayley-III-Scales.
  • - Results indicate that SGA infants exhibited more immature EEG patterns, and several EEG characteristics were linked to lower developmental scores, suggesting a connection between low birthweight and neurological development issues.
View Article and Find Full Text PDF

Background: To analyze the findings in the background EEG activity of infants who suffered perinatal stroke.

Methods: Eleven neonates born 2009-2014 diagnosed of ischemic stroke by MRI (three of them with multistroke) underwent continuous video-EEG monitoring. Visual and spectral (power spectrum and coherence) analyses of the background EEG was performed in three moments: 1) Onset of EEG recording (prior to initiate seizure treatment), 2) Post-ictal epoch (1-2 h after the last seizure), and 3) one-two days after seizure control.

View Article and Find Full Text PDF

Background: What constitutes a "normal" background electroencephalography (EEG) rhythm immediately after birth is not well understood. We performed video-electroencephalography recordings in the first six hours (first measure) and the third day of life (second measure) for evidence of transient changes in brain function.

Methods: We performed a cohort study of an incidental sample of healthy term neonates in a single-center nursery.

View Article and Find Full Text PDF

Objective: To determine whether full-term newborn infants of diabetic mothers (IDM) present immature/disorganised EEG patterns in the immediate neonatal period, and whether there was any relationship with maternal glycaemic control.

Design And Setting: Cohort study with an incidental sample performed in a tertiary hospital neonatal unit.

Patients: 23 IDM and 22 healthy newborns born between 2010 and 2013.

View Article and Find Full Text PDF

We present 2 term newborn infants with apneic seizure originating in the occipital lobe that was diagnosed by video-EEG. One infant had ischemic infarction in the distribution of the posterior cerebral artery, extending to the cingulate gyrus. In the other infant, only transient occipital hyperechogenicity was observed by using neurosonography.

View Article and Find Full Text PDF

This report presents a case of superficial siderosis of the central nervous system secondary to repeated intraventricular and subarachnoid bleeding of a newborn infant with neonatal alloimmune thrombocytopenia. In addition, this infant manifested Dandy-Walker variant. To date, the few known cases of superficial siderosis in neonates have not been associated with neonatal alloimmune thrombocytopenia or Dandy-Walker complex.

View Article and Find Full Text PDF

Objective: Clinical significance of neonatal positive temporal sharp waves (PTS) is controversial. The aim of this work is to study (1) PTS incidence in preterm infants with or without major ultrasound lesion (MUL) per gestational age (GA), and (2) the relationship between PTS in both sleep states and other electroencephalographic (EEG) findings with poor prognoses.

Methods: 97 preterm infants of <27-36 weeks GA, and 12 full-term healthy infants were presented.

View Article and Find Full Text PDF