Publications by authors named "Jose Pecori-Giraldi"

Background: To compare the usefulness of the traditional pattern-reversal Visual Evoked Potentials (VEP) with multifocal VEP (mfVEP) and Frequency-Doubling Technology (FDT) perimetry in the evaluation of the ocular abnormalities induced by acute or subacute optic neuritis (ON).

Materials And Methods: The test results of 24 ON patients were compared with those obtained in 40 normal control subjects. MfVEP recordings were obtained by using an Optoelectronic Stimulator that extracts topographic VEP using a pseudorandom m-sequence stimulus.

View Article and Find Full Text PDF

Background: The purpose of this study was to demonstrate the hypotensive efficacy and tolerability of latanoprost when used as monotherapy and as polytherapy associated with antiglaucomatous medication proven to be ineffective in keeping intraocular pressure under control.

Methods: Three hundred and thirty-seven patients (672 eyes) affected by primary open-angle glaucoma and intraocular hypertension were recruited over a period of 10 years from the Glaucoma Centre, Department of Ophthalmological Sciences, University of Rome "Sapienza", and treated, subject to informed consent, with latanoprost 0.005% alone or in combination with other ocular hypotensive drugs.

View Article and Find Full Text PDF

Purpose: The purpose of the study was to assess the effect of ibopamine (3,4 di-isobutyrrylester of N-methyldopamine), a D1-dopamine agonist, on intraocular pressure (IOP) in offspring of parents with primary openangle glaucoma as a consequence of outflow structures impairment.

Materials And Methods: We included participants aged between 8 and 40 years: group 1, 163 offspring of at least 1 parent with primary openangle glaucoma with normal IOP and without glaucomatous damages; group 2, 108 offspring of healthy parents (without history or existing glaucoma). Ibopamine test was performed by instilling 2 drops, 5 minutes apart, in both eyes followed by repeated IOP measurements over a 45-minute period.

View Article and Find Full Text PDF

Synopsis of recent research by authors named "Jose Pecori-Giraldi"

  • - Jose Pecori-Giraldi's research primarily focuses on advanced diagnostic techniques for ocular conditions, particularly in the fields of optic neuritis and glaucoma.
  • - His findings suggest that multifocal visual evoked potentials (mfVEP) and Frequency-Doubling Technology (FDT) perimetry may offer enhanced evaluation of ocular abnormalities compared to traditional methods.
  • - The studies he conducted also demonstrate the efficacy and safety of using latanoprost in managing intraocular pressure in glaucoma patients, as well as the potential role of ibopamine in diagnosing glaucoma among high-risk populations.