Publications by authors named "Jose Paz Jimenez"

Article Synopsis
  • The study utilized a (HR)-ICP-MS method to analyze metallic alloy components (Ti, V, Cr, Co, Ni, Mo) in the blood and urine of patients with hip and knee prostheses.
  • It compared these levels to a control group of patients without metallic implants, showing that most metal concentrations were similar between the two groups.
  • Elevated titanium levels were specifically noted in the urine and blood of patients with titanium alloy prostheses, highlighting the effectiveness of this multielement analysis in complex biological samples.
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A sector field high-resolution (HR)-ICP-MS and an octapole reaction system (ORS)-ICP-MS have been compared for the simultaneous determination of traces of metals (Ti, V, Cr, Co, Ni, and Mo) released from dental implants and articular prostheses in human biological fluids. Optimum sample treatments were evaluated to minimize matrix effects in urine and whole blood. Urine samples were diluted tenfold with ultrapure water, whereas whole blood samples were digested with high-purity nitric acid and hydrogen peroxide and finally diluted tenfold with ultrapure water.

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Internal fixation with a Gamma nail, in its short and long versions, is an excellent surgical technique for intertrochanteric and subtrochanteric fractures of the femur. A stable osteosynthesis is obtained which allows early mobilisation and promotes healing of the fracture. However, it is not free from complications; many of them are due to poor surgical technique and/or inadequate monitoring.

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Background: The impact of vitamin D receptor (VDR) gene polymorphisms in bone metabolism remains controversial. Some authors have found a beneficial effect of some VDR gene polymorphisms, while others found no differences, or even a lower bone mass in subjects with the same type of polymorphisms. The aim of this study was to assess if the VDR gene polymorphisms could have an effect on the calcitriol-stimulated osteocalcin in human osteoblasts.

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