Publications by authors named "Jose Naval-Alvarez"

Background: Despite their frequency and potential impact on prognosis, cancers diagnosed via self-referral to the emergency department are poorly documented. We conducted a detailed analysis of cancer patients diagnosed following emergency self-referral and compared them with those diagnosed following emergency referral from primary care. Given the challenges associated with measuring intervals in the emergency self-referral pathway, we also aimed to provide a definition of the diagnostic interval for these cancers.

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Article Synopsis
  • The study examined the relationship between the number of primary care consultations and the time taken from initial presentation to cancer diagnosis in emergency cases compared to nonemergency cases.
  • It found a strong correlation in emergency patients where a higher number of consultations often resulted in longer diagnostic intervals, particularly for certain cancer types like pancreatic and lung cancers.
  • The results indicate a need for system-level interventions to minimize delays in diagnosis for cancer patients who have had multiple consultations prior to emergency referral.
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Article Synopsis
  • The study investigates how long it takes for cancer patients to get diagnosed after they first notice symptoms, comparing emergency presentations to those who go through primary care.
  • Data was gathered from outpatients diagnosed with 15 types of solid cancers over five years, focusing on the time taken from first symptoms to diagnosis based on the route of presentation.
  • Findings show that patients diagnosed through emergency services had shorter intervals than those through primary care, but those with multiple prior consultations in primary care had similar intervals to those diagnosed in primary care, indicating that previous visits can significantly affect diagnosis timing.
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The "legacy effect" describes the long-term benefits that may persist for many years after the end of an intervention period, involving different biological processes. The legacy effect in cardiovascular disease (CVD) prevention has been evaluated by a limited number of studies, mostly based on pharmacological interventions, while few manuscripts on dietary interventions have been published. Most of these studies are focused on intensive treatment regimens, whose main goal is to achieve tight control of one or more cardiovascular risk factors.

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