Analysis of the use of codon pairs in the HE gene of the ISA virus shows a correlation between bias in HPR codon-pair use and mortality rates caused by the virus.

Background: Segment 6 of the ISA virus codes for hemoagglutinin-esterase (HE). This segment is highly variable, with more than 26 variants identified. The major variation is observed in what is called the high polymorphism region (HPR).

Purification and characterization of the antimicrobial peptide microcin N.

Microcins are low-molecular-weight proteins secreted by certain bacteria that act by limiting the growth of other bacteria that share the same ecological niche. In the present work, the previous microcin 24 system was resequenced.We detected three nucleotide differences in the microcin-coding gene that partially change the amino acid sequence.