Assessment of cognitive games to improve the quality of life of Parkinson's and Alzheimer's patients.

Objectives: The core objectives of this study centre on enhancing the quality of life and well-being of individuals diagnosed with Parkinson's and Alzheimer's diseases. Our aim is to facilitate the monitoring of patient information, benefiting both caregivers and healthcare professionals.

Methods: As part of the PROCare4Life platform sensorial ecosystem, a web application with six engaging cognitive games focusing on developing cognitive training and stimulating brain activity are developed.

Synthesis of High Sn Content GeSiSn (0.1 < < 0.22) Semiconductors on Si for MWIR Direct Band Gap Applications.

A systematic effort has been described to grow ternary GeSiSn semiconductors on silicon with high Sn concentrations spanning the 9.5-21.2% range.

Novel PWO/ ZnO heterostructured nanocomposites: Synthesis, characterization, and photocatalytic performance.

Photocatalytic degradation is becoming an increasingly attractive method for addressing environmental remediation challenges. In this work, the novel pure PWO/ZnO and doped PWO: Er/ZnO: Ag heterostructure nanocomposites with premier photocatalytic efficiency were synthesized via a simple co-precipitation method followed by a solvothermal procedure. X-ray diffraction (XRD), diffuse reflectance spectroscopy (DRS), X-ray photoelectron spectroscopy (XPS), high-resolution transmission electron microscopy (HRTEM), energy dispersive X-ray (EDX), and ultraviolet-visible (UV-Vis) absorbance measurements techniques were employed to characterize the structural and optical properties.

Cardiac surgery simulation: Advances in transvenous lead extraction.

The clinical importance of procedures for transvenous lead extraction has increased greatly because the volume of cardiac implantable electronic devices has increased. Consequently, the number of device-related complications requiring lead extraction has also been increasing. Great improvements in lead extraction techniques have occurred in recent years with the development of transvenous lead extraction tools and techniques.

The development of a clinical algorithm for the diagnosis of tumours in the parapharyngeal space. A systematic review.

Introduction: Parapharyngeal space (PPS) is defined as a deep space, located around the upper pharynx, in the shape of an inverted pyramid. Primary tumours in this region are rare, accounting for 0.5% of head and neck neoplasms, and most are benign.

Ultrasound-guided Drainage vs Surgical Drainage of Deep Neck Space Abscesses: A Randomized Controlled Trial.

Introduction: The most common cause of deep neck infections is dental infection. They are diagnosed with physical examination, imaging studies, ultrasound, or computed tomography. Surgical drainage of collections should always be performed early in a classical or percutaneous way, depending on the case.

Enantioselective Synthesis and Pharmacological Evaluation of Aza-CGP37157-Lipoic Acid Hybrids for the Treatment of Alzheimer's Disease.

Hybrids based on an aza-analogue of CGP37157, a mitochondrial Na/Ca exchanger antagonist, and lipoic acid were obtained in order to combine in a single molecule the antioxidant and NRF2 induction properties of lipoic acid and the neuroprotective activity of CGP37157. The four possible enantiomers of the hybrid structure were synthesized by using as the key step a fully diastereoselective reduction induced by Ellman's chiral auxiliary. After computational druggability studies that predicted good ADME profiles and blood-brain permeation for all compounds, the DPPH assay showed moderate oxidant scavenger capacity.

Ultralight-Weight Graphene Aerogels with Extremely High Electrical Conductivity.

The integration of 2D graphene sheets into a porous and macroscopic structure is extremely attractive for application in several electrochemical fields. In this regard, for the first time, the synthesis of 3D graphene aerogels is reported by using a rapid, easy, cost-effective, and scalable at industrial level methodology. These aerogels integrate the intrinsic properties of graphene with a high pore volume.

Ultrasound-guided drainage vs surgical drainage of deep neck space abscesses: A randomized controlled trial.

Introduction: The most common cause of deep neck infections is dental infection. They are diagnosed with physical examination, imaging studies, ultrasound, or computed tomography. Surgical drainage of collections should always be performed early in a classical or percutaneous way, depending on the case.

The development of a clinical algorithm for the diagnosis of tumours in the parapharyngeal space. A systematic review.

Introduction: Parapharyngeal space (PPS) is defined as a deep space, located around the upper pharynx, in the shape of an inverted pyramid. Primary tumours in this region are rare, accounting for 0.5% of head and neck neoplasms, and most are benign.

Haptic Glove TV Device for People with Visual Impairment.

Immersive video is changing the way we enjoy TV. It is no longer just about receiving sequential images with audio, but also playing with other human senses through smells, vibrations of movement, 3D audio, feeling water, wind, heat, and other emotions that can be experienced through all human senses. This work aims to validate the usefulness of an immersive and interactive solution for people with severe visual impairment by developing a haptic glove that allows receiving signals and generating vibrations in hand, informing about what happens in a scene.

Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties.

Two multitarget hybrids, derived from an aza-analogue of CGP37157, a mitochondrial Na /Ca exchanger antagonist, and lipoic acid were designed in order to combine in a single molecule the antioxidant and Nrf2 induction properties of lipoic acid and the neuroprotective activity of CGP37157. The hybrid derivatives showed Nrf2 induction and radical scavenging properties, leading to a good neuroprotective profile against oxidative stress, together with an interesting antineuroinflammatory activity. The results obtained show differences in activity depending on the configuration of the chiral center of LA.

Three-D Wide Faces (3DWF): Facial Landmark Detection and 3D Reconstruction over a New RGB⁻D Multi-Camera Dataset.

Latest advances of deep learning paradigm and 3D imaging systems have raised the necessity for more complete datasets that allow exploitation of facial features such as pose, gender or age. In our work, we propose a new facial dataset collected with an innovative RGB⁻D multi-camera setup whose optimization is presented and validated. 3DWF includes 3D raw and registered data collection for 92 persons from low-cost RGB⁻D sensing devices to commercial scanners with great accuracy.

On the influence of low-level visual features in film classification.

Background: In this paper we present a model of parameters to aesthetically characterize films using a multi-disciplinary approach: by combining film theory, visual low-level video descriptors (modeled in order to supply aesthetic information) and classification techniques using machine and deep learning.

Methods: Four different tests have been developed, each for a different application, proving the model's usefulness. These applications are: aesthetic style clustering, prediction of production year, genre detection and influence on film popularity.

Influence of age and spectral power distribution on mesopic visual sensitivity.

The ability of the human visual system to detect stimuli at low illumination levels provides awareness of potential risks. The influence of age and spectral power distribution on mesopic spectral sensitivity is analyzed. Two typical light sources are used, a high-pressure sodium lamp (HPS), with a higher content of long wavelengths, and a metal halide lamp (MH), with a higher content of short wavelengths.

Fabrication of Ge:Ga Hyperdoped Materials and Devices Using CMOS-Compatible Ga and Ge Hydride Chemistries.

We report a versatile chemical vapor deposition (CVD) method to dope Ge films with Ga atoms in situ over a wide concentration range spanning from 3 × 10 to 2.7 × 10 cm. The method introduces a stable and volatile Ga hydride [DGaN(CH)] that reacts readily with GeH to deliver Ga dopants controllably and systematically at complementary metal-oxide-semiconductor compatible ultralow temperatures of ∼360 °C.

Correction: Improving vehicle tracking rate and speed estimation in dusty and snowy weather conditions with a vibrating camera.

[This corrects the article DOI: 10.1371/journal.pone.

Robust vehicle detection in different weather conditions: Using MIPM.

Intelligent Transportation Systems (ITS) allow us to have high quality traffic information to reduce the risk of potentially critical situations. Conventional image-based traffic detection methods have difficulties acquiring good images due to perspective and background noise, poor lighting and weather conditions. In this paper, we propose a new method to accurately segment and track vehicles.

Improving vehicle tracking rate and speed estimation in dusty and snowy weather conditions with a vibrating camera.

Traffic surveillance systems are interesting to many researchers to improve the traffic control and reduce the risk caused by accidents. In this area, many published works are only concerned about vehicle detection in normal conditions. The camera may vibrate due to wind or bridge movement.

Synthesis and Structural and Optical Properties of Ga(AsP)Ge and (GaP)Ge Semiconductors Using Interface-Engineered Group IV Platforms.

Epitaxial synthesis of Ga(AsP)Ge alloys on Si(100) substrates is demonstrated using chemical vapor deposition reactions of [DGaN(CH)] with P(GeH) and As(GeH) precursors. These compounds are chosen to promote the formation of GaAsGe and GaPGe building blocks which interlink to produce the desired crystalline product. Ge-rich (GaP)Ge analogues have also been grown with tunable Ge contents up to 90% by reactions of P(GeH) with [DGaN(CH)] under similar deposition protocols.

Observation of Phase-Filling Singularities in the Optical Dielectric Function of Highly Doped n-Type Ge.

Phase-filling singularities in the optical response function of highly doped (>10^{19}  cm^{-3}) germanium are theoretically predicted and experimentally confirmed using spectroscopic ellipsometry. Contrary to direct-gap semiconductors, which display the well-known Burstein-Moss phenomenology upon doping, the critical point in the joint density of electronic states associated with the partially filled conduction band in n-Ge corresponds to the so-called E_{1} and E_{1}+Δ_{1} transitions, which are two-dimensional in character. As a result of this reduced dimensionality, there is no edge shift induced by Pauli blocking.

Ultralow Resistivity Ge:Sb heterostructures on Si Using Hydride Epitaxy of Deuterated Stibine and Trigermane.

The nonconventional deuterated stibine (SbD3) compound has been used for the first time in combination with trigermane (Ge3H8) to produce hyper-doped Ge-on-Si films with carrier concentrations n > 10(20) cm(-3) and record-low resistivities ρ = 1.8 × 10(-4) Ω cm. The growth takes place on Ge and Ge1-xSix buffered Si(100) wafers at ultralow temperatures (∼330 °C) at which Sb diffusion is negligible, leading to extremely flat atomic profiles of the constituents.

A Sustainable Approach to the Stereoselective Synthesis of Diazaheptacyclic Cage Systems Based on a Multicomponent Strategy in an Ionic Liquid.

The microwave-assisted three-component reactions of 3,5-bis(E)-arylmethylidene]tetrahydro-4(1H)-pyridinones, acenaphthenequinone and cyclic α-amino acids in an ionic liquid, 1-butyl-3-methylimidazolium bromide, occurred through a domino sequence affording structurally intriguing diazaheptacyclic cage-like compounds in excellent yields.