Superoxidase dismutase (SOD) topical use in oncologic patients: treatment of acute cutaneous toxicity secondary to radiotherapy.

Objective: The objective of this study is to evaluate the efficiency of SOD applied topically in oncologic patients affected by acute radiodermatitis.

Materials And Method: This study includes 57 patients who showed a dermatitis grade 2 or superior; they were administered SOD ointment b.i.

Early stage breast cancer conserving treatment: high dose rate brachytherapy boost to the tumour bed.

Introduction: The dose administered to the tumour bed is a risk-factor for local recurrence in localised breast cancer following breast-conserving surgery.

Materials And Methods: All patients (n=94) received 50 Gy external beam radiotherapy and one application of 700 cGy at 85% isodose with high dose rate brachytherapy.

Results: Of the cases, 84% were infiltrating ductal carcinoma; 31.