Severe thrombocytopenia induced by iodinated contrast after coronary angiography: The use of gadolinium contrast and intravascular ultrasound as an alternative to guide percutaneous coronary intervention.

Acute contrast-induced thrombocytopenia is a rare event with the use of modern low osmolarity iodinated contrast media. The pathophysiological mechanism that causes platelet counts to drop has not been identified, but an immunological mechanism is suspected due to cytotoxicity after previous exposure to contrast. We report the case of a 47-year-old male patient with acute severe thrombocytopenia due to iodinated contrast media exposure.

[Clinical trial of radial artery compression guided by mean arterial pressure].

Objective: To determine whether a compression procedure guided by the patient's mean arterial pressure value (experimental) is safe and effective and superior to a compression procedure using 15 cubic centimeters of air in the device (standard) in patients undergoing radial artery catheterization.

Methods: We performed a randomized, single-center study, which included patients undergoing catheterization of the radial artery for diagnosis or percutaneous coronary intervention, in whom the sheath was removed at the end of procedure and the radial artery was compressed for 3 h with a pneumatic device (TR Band Terumo). The arteries were evaluated between 24 and 72 h after the procedure, using a plethysmography curve with a reverse flow test followed by bidirectional Doppler.