Publications by authors named "Jose Manuel De La Morena"
Introduction: High grade, non-muscle invasive bladder cancer (NMIBC) is usually treated with intravesical Bacillus Calmette-Guérin. Chemohyperthermia therapy (CHT) may be a novel alternative therapy for the treatment of NMIBC.
Objective: To evaluate the recurrence-free survival (RFS) of patients treated with CHT using the Combat bladder recirculation system (BRS) for NMIBC.
Article Synopsis
- 1. Background: The study explores the effectiveness of hyperthermic intravesical chemotherapy (HIVEC) using mitomycin-C (MMC) as an alternative treatment for non-muscle invasive bladder cancer (NMIBC), especially during a shortage of BCG therapy.
- 2. Methods: Researchers conducted an observational trial (HIVEC-E) on NMIBC patients in Spain from 2012 to 2020, evaluating treatment outcomes like recurrence, progression, and overall mortality, while monitoring safety and adverse effects.
- 3. Results: 502 patients received a median of 8.78 HIVEC MMC treatments over a follow-up of about 24.5 months,
Objective: To evaluate the coronavirus disease 2019 perioperative infection rate and mortality rate of patients undergoing urological surgeries during the early pandemic period in Spain.
Methods: This was a non-interventional multicenter prospective study carried out from 9 March to 3 May 2020 in two urology departments in Madrid, Spain. Clinical, microbiological and radiological data of patients who underwent surgery were collected from computerized medical records.
Objectives: To assess the adherence to the antibiotic prophylaxis protocol in patients undergoing prostate surgery and evaluate the effect of antibiotic prophylaxis on surgical site infections (SSI).
Material And Methods: A prospective cohort study was carried out between January 2009 and September 2016. The global compliance with the antibiotic prophylaxis protocol was evaluated studying the items: time of onset, route of administration, antibiotic prescribed, duration and dose.
We describe the first clinical case in the reviewed literature of a patient with a complicated renal cyst by fistula of an appendicular neoplasm with acute appendicitis, as well as the management performed and the therapeutic options in similar cases.
View Article and Find Full Text PDFIn this article we review the most significant published papers on active surveillance in prostate cancer and present the results of our case series. We used as main response variables the percentage of patients remaining in surveillance and the oncological results presented as global, cancer specific and metastasis free survivals. Globally, in published series 71.
View Article and Find Full Text PDFObjectives: Nephron-sparing surgery (NSS ) has been considered throughout history for patients with solitary kidney, bilateral renal tumors, impaired renal function (RF), and hereditary renal cancer. However, recently the indications for Partial Nephrectomy (PN ) have extended and include patients with a healthy contralateral kidney. NSS has evolved in a great way during the last decade, specifically in terms of oncological indications, and in the renal ischemia time used with the goal to maintain as much renal function as possible.
View Article and Find Full Text PDFObjectives: To review the value of PSA kinetics in the diagnosis and prognosis of prostate cancer.
Methods: Review of the literature through a Medline search.
Conclusions: A pre-tretament PSAV value >2ng/ ml/yr is a risk factor for increased mortality from prostate cancer after surgery or radiation therapy.