Publications by authors named "Jose Malavet"
Background: Patients with obesity, especially those suffering from obstructive sleep apnea (OSA), are prone to postoperative respiratory hypoxemia. The PRODIGY (prediction of opioid-induced respiratory depression in patients monitored by capnography) Score is used to predict respiratory complications that factor in sleep-disordered breathing. Data on the impact of OSA on the frequency and timing of postoperative desaturation trends after bariatric surgery are lacking.
View Article and Find Full Text PDFSex-based differences in candidacy for transcatheter tricuspid valve intervention.
Catheter Cardiovasc Interv
October 2024
Article Synopsis
- - Women have a higher prevalence of tricuspid regurgitation (TR) and tend to present with more advanced stages of the condition compared to men, leading to the exploration of sex-based differences in eligibility for transcatheter tricuspid valve interventions (TTVI).
- - A study of 569 patients revealed that while men exhibited more left ventricular dysfunction and heart failure signs, women were more likely to experience isolated TR and TR linked to severe pulmonary hypertension.
- - Despite differences in presenting conditions, the majority of patients were not eligible for TTVI, and sex did not significantly impact eligibility for the procedure.
Background: More than moderate tricuspid regurgitation (TR) is associated with high mortality. Surgical tricuspid valve repair and replacements are rarely performed due to high operative mortality risk, mainly attributed to late presentation. Novel transcatheter tricuspid valve intervention (TTVI) devices are being developed as an alternative to surgery.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the prognostic value of the blood urea nitrogen to serum albumin ratio (BAR) in predicting outcomes for lung cancer patients who undergo robotic-assisted pulmonary lobectomy (RAPL).
- An analysis of 400 patients revealed that while there was a clear threshold for BAR, there were no significant differences in surgical complications or 30-day mortality outcomes between those with Low and High BAR.
- The conclusion is that High BAR does not effectively predict worse outcomes in this context, suggesting the need for further research to explore its prognostic capabilities in lower-risk patient populations.
Background: Outcomes of lung cancer patients traveling greater distances for surgical oncology care are not well-described. We investigated the effects of increased travel burden after robotic-assisted pulmonary lobectomy (RAPL) for lung cancer.
Methods: Clinical characteristics and surgical outcomes of 711 consecutive patients who underwent RAPL from September 2010 to March 2022 were compared, stratified by primary residential ZIP code <160 km or ≥160 km from the cancer center.
Article Synopsis
- The COVID-19 pandemic created challenges for patients seeking healthcare, prompting a study on its impact on outcomes for patients undergoing robotic-assisted pulmonary lobectomy (RAPL).
- Researchers analyzed data from 721 patients, categorizing them into those treated before and during the pandemic to assess various health factors and surgical results.
- Findings revealed that although COVID-19-Era patients had more preoperative health issues, they experienced lower intraoperative blood loss and reduced rates of new-onset atrial fibrillation, suggesting RAPL remained a safe procedure during this time, though further investigation into risks of postoperative complications like empyema is warranted.
Doxorubicin is a widely used and effective chemotherapy, but the major limiting side effect is cardiomyopathy which in some patients leads to congestive heart failure. Genetic variants in have been associated with the development of doxorubicin-induced cardiotoxicity, suggesting that TRPC6 may be a therapeutic target for cardioprotection in cancer patients. Assessment of deficiency to prevent doxorubicin-induced cardiac damage and function was conducted in male and female B6.
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