Use of polyphenols as a strategy to prevent bond degradation in the dentin-resin interface.

This study evaluated the effect of dentin pretreatment with the polyphenols quercetin and resveratrol on the resin-dentin microtensile bonding strength (μTBS) and collagen fibrils stability of the adhesive interface. Different concentrations (100, 250, 500, or 1,000 μg ml ) of quercetin or resveratrol, or a mixture of quercetin and resveratrol (3:1, 1:1, 1:3; vol:vol), as well as distilled water or 2% chlorhexidine digluconate, were applied to etched dentin. Then, a two-step etch-and-rinse adhesive was applied followed by composite restoration.