Publications by authors named "Jose M Quintilla"
Article Synopsis
- Clinical trials for pediatric patients are complex, especially with decentralized designs, and high-realistic simulations can help refine processes and improve interactions among professionals, patients, and families.
- This research examined how simulations affected three critical stages of a clinical trial: the initial visit, home drug administration by parents, and pharmacokinetics sample processing by a home nurse.
- The findings showed that while families could administer the drug as required, they faced challenges, and recommendations were provided to enhance safety and patient experience in future trials, highlighting the value of simulation to proactively identify risks and improve protocols before finalization.
Purpose: Real-time MRI-guided laser interstitial thermal therapy (LITT) is a challenging procedure due to its technical complexity, as well as the need for efficient multidisciplinary teamwork and transfer of an anesthetized patient between operating room (OR) and magnetic resonance (MR). A highly realistic simulation was developed to design the safest process before being applied to real patients. In this report, authors address the description of the methodology used for this simulation and its purposefulness.
View Article and Find Full Text PDFObjectives: The objectives of this study were (1) to validate the Alvarado score and pediatric appendicitis score (PAS) in a prospectively identified pediatric cohort and (2) to assess abdominal ultrasonography (AUS) as a tool to increase the diagnostic reliability of both scores.
Patients And Methods: Prospective study conducted from January 10, 2008, to January 1, 2009. All patients attended at the emergency department with suspected acute appendicitis (AA) who had a blood sample collected were included.