Hemodynamic effects of dexmedetomidine--fentanyl vs. nalbuphine--propofol in plastic surgery.

Unlabelled: Dexmedetomidine has demonstrated to be useful in several clinical fields due to its respiratory safety and cardiovascular stability. We undertook this study to determine its usefulness in plastic surgery. Sixty patients were divided into two parallel groups.

Acute effect of the transdermal administration of nicotine on insulin sensitivity in healthy individuals with and without a family history of type 2 diabetes mellitus in the first branch.

The aim of this study was to evaluate the acute effect of the transdermal administration of nicotine on insulin sensitivity in healthy individuals with and without family histories of type 2 diabetes mellitus (DM2) in the first branch. A randomized, double-blind, cross-over, placebo-controlled clinical trial with two parallel groups was carried out in 12 healthy individuals, six with a family history of diabetes and six without such family history. The volunteers were randomly assigned to administration of a nicotine or placebo patch and were crossed-over with a difference of at least 3 days between each patch.

Adipokines and insulin resistance during pregnancy.

Normal pregnancy has been characterized as a "diabetogenic state". On the other hand, the adipose tissue is now considered an active organ, capable of secreting substances such as adipokines, which may play a role in the pathogenesis of insulin resistance. Resistin, leptin serum and placental levels increase as pregnancy progresses, which is in contrast to levels of adiponectin.

[Effect of a high fat or high carbohydrate breakfast on postprandial lipid profile in healthy subjects with or without family history of type 2 diabetes mellitus].

The objective of this study was to evaluate the effect of a high fat or high carbohydrate breakfast on postprandial lipid profile in healthy subjects with or without family history of type 2 diabetes mellitus. A single blind, controlled clinical trial with parallel groups was performed in 20 healthy subjects; 10 subjects with family history of type 2 diabetes mellitus and 10 individuals without that background. Each group was randomized to receive a high fat or high carbohidrate breakfast.