Neuronal progenitors of the dentate gyrus express the SARS-CoV-2 cell receptor during migration in the developing human hippocampus.

The COVID-19 pandemic spread around the world is due to the enormous capacity of the SARS-CoV-2 coronavirus to be transmitted between humans, causing a threat to global public health. It has been shown that the entry of this virus into cells is highly facilitated by the presence of angiotensin-converting enzyme 2 (ACE2) in the cell membrane. Currently, we have no precise knowledge of how this receptor expresses in the brain of human fetus and, as a consequence, we do not know how susceptible the neural cells in the developing brain are to being infected through the vertical transmission of this virus, from mother to fetus.

[ACE2 expression in the brain during development and susceptibility to brain infection by SARS-CoV-2].

The COVID-19 pandemic spread around the world due to the enormous transmission of the SARSCoV-2 among humans. COVID-19 represents a threat to global public health. The entry of this virus into cells is greatly facilitated by the presence of angiotensin-converting enzyme 2 (ACE2) in the cell membrane.

[Convergent validity of two tests of conscientiousness].

Convergent validity of two tests of conscientiousness. The absence of correspondence between objective measurement of behavior and measurement based on self-report along with generalized use of questionnaires as personality assessment instruments raises a problem with regard to the validity of assessment instruments in this area of study. The goal of this work is to obtain a convergent validity measure for an objective assessment computerized task of conscientiousness based on the development of a functional equally but morphologically different task.