Publications by authors named "Jose M Gastelum-Cano"

Background: Fungal endocarditis is a low-frequency disease with a challenging diagnosis, as it can be mistaken with bacterial endocarditis. Fungal endocarditis causes higher mortality rates in immunocompromised patients. In the clinical practice, the endocarditis caused by fungi represents up to 10% of all infectious endocarditis cases and has a mortality rate of nearly 50%.

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Coccidioidomycosis is a systemic disease caused by the fungi Coccidioides immitis and C. posadasii. It is a prevalent disease in arid regions with high temperatures and low precipitations in America.

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Here we described a case of an asymptomatic 73 years-old female patient in geriatric routine consultation, whose laboratory testing showed hyperproteinemia with accompanying hyperglobulinemia. A diagnosis of BGUS was made only after a correlation among SPEP, densitometry tracing and IFE results was established, evidencing a second peak, that was less evident and not reported at first. These biclonal conditions are of very low incidence in the clinical laboratory, requiring the laboratory professional to have particular skills for their identification.

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Article Synopsis
  • GFR is already impaired in MS patients, and chemotherapy with cyclophosphamide can worsen it.
  • Four out of 28 MS patients had chronic kidney disease before chemotherapy, and after treatment, 12 exhibited abnormal GFR results.
  • Close monitoring of renal function is crucial for MS patients receiving stem-cell transplantation, and minimizing chemotherapy dosage is recommended to protect kidney health.
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