[Bacterial infections in COVID-19 patients hospitalized in intensive care unit].

In this brief communication, we retrospectively describe COVID-19 severe patient's characteristics in ICU, and report 37,6% of secondary bacterial infections, mainly with nosocomial respiratory infections and rarely from community source.

Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Lactate Levels on 28-Day Mortality Among Patients With Septic Shock: The ANDROMEDA-SHOCK Randomized Clinical Trial.

Importance: Abnormal peripheral perfusion after septic shock resuscitation has been associated with organ dysfunction and mortality. The potential role of the clinical assessment of peripheral perfusion as a target during resuscitation in early septic shock has not been established.

Objective: To determine if a peripheral perfusion-targeted resuscitation during early septic shock in adults is more effective than a lactate level-targeted resuscitation for reducing mortality.

Envelope analysis of the airflow signal to improve polysomnographic assessment of sleep disordered breathing.

Study Objectives: Given the detailed respiratory waveform signal provided by the nasal cannula in polysomnographic (PSG) studies, to quantify sleep breathing disturbances by extracting a continuous variable based on the coefficient of variation of the envelope of that signal.

Design: Application of an algorithm for envelope analysis to standard nasal cannula signal from actual polysomnographic studies.

Setting: PSG recordings from a sleep disorders center were analyzed by an algorithm developed on the Igor scientific data analysis software.