Vasomotor response to different endothelium-dependent vasodilators in an animal model.

Background And Objectives: Incomplete re-endothelialization of stents can be revealed as paradoxical vasoconstriction with endothelium-dependent vasodilators. As no consensus exists about the best method or agent, our objective is to analyze the response to different drugs in a coronary swine model.

Methods: Twenty-seven stents were implanted in 9 domestic swine.