Publications by authors named "Jose Luis Pontones"

Background: After exhausting other therapeutic options, pelvic exenteration is performed in patients who suffer from relapsed gynaecologic tumours, with most of them requiring some sort of urinary diversion.

Material And Methods: The main objective of this study was to assess the short- and medium/long-term urinary complications associated with the Bricker ileal conduit versus double-barrelled wet colostomy after performing a pelvic exenteration for gynaecologic malignancies.

Results: A total of 61 pelvic exenterations were identified between November 2010 and April 2022; 29 Bricker ileal conduits and 20 double-barrelled wet colostomies were included in the urinary diversion analysis.

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Article Synopsis
  • 1. Background: The study explores the effectiveness of hyperthermic intravesical chemotherapy (HIVEC) using mitomycin-C (MMC) as an alternative treatment for non-muscle invasive bladder cancer (NMIBC), especially during a shortage of BCG therapy.
  • 2. Methods: Researchers conducted an observational trial (HIVEC-E) on NMIBC patients in Spain from 2012 to 2020, evaluating treatment outcomes like recurrence, progression, and overall mortality, while monitoring safety and adverse effects.
  • 3. Results: 502 patients received a median of 8.78 HIVEC MMC treatments over a follow-up of about 24.5 months,
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Malignant triton tumor (MTT) is a variant of the peripheral nerve sheath tumor. It is very uncommon but shows an aggressive course and limited survival. Half of the cases present symptoms related to neurofibromatosis type 1 disease.

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Background: Superficial bladder cancer has been the subject of numerous studies for many years, but the evolution of the disease still remains not well understood. After the tumor has been surgically removed, it may reappear at a similar level of malignancy or progress to a higher level. The process may be reasonably modeled by means of a Markov process.

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Objectives: Three-dimensional (3D) spheroids are a good model for studying in vitro chemosensitivity because they reproduce unicellular and multicellular mechanisms of drug resistance. We aimed to develop a chemosensitivity test for intravesical drugs and to also verify the effects of verapamil (VPM) and ciprofloxacin (CIPRO).

Methods: Cold cup biopsies from 40 superficial bladder tumours were taken, fragmented, and left in culture.

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Infective endocarditis (IE) presents with several signs and symptoms that are mainly heart-related and the result of bacteremia. We describe the case of a woman with severe renal hemorrhage due to a septic embolic cortical infarction, who was also receiving anticoagulation therapy because of cardiopathy, whose retroperitoneal hematoma was the first manifestation of IE.

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