Publications by authors named "Jose L Ribes"
Background/objectives: The relationship between macronutrient intake and cognitive decline in older adults with type 2 diabetes mellitus (T2DM) remains underexplored.
Methods: This cross-sectional study aimed to evaluate the association between the protein-to-carbohydrate energy ratio (%E:P) and cognitive impairment among 192 elderly T2DM patients. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and the Self-Administered Gerocognitive Exam (SAGE), while dietary intake data, including (%E:P), was gathered using a validated semi-quantitative food frequency questionnaire.
Article Synopsis
- A study on 219 older patients with type 2 diabetes aimed to investigate the relationship between liver fibrosis, liver steatosis, and cognitive impairment.
- Results showed that a significant number of patients had mild cognitive impairment (53.88%) or dementia (16.43%), and those with moderate to high risks of liver fibrosis were more likely to have cognitive issues.
- The study concluded that liver fibrosis, indicated by a FIB-4 score greater than 1.54, is linked to cognitive impairment, suggesting it could be a potential biomarker for detecting cognitive decline in older diabetes patients.
Article Synopsis
- Type 2 diabetes mellitus currently affects 10.5% of adults worldwide, with predictions showing that by 2045, it could rise to one in eight adults, while mild cognitive impairment affects 19.7% of adults aged 50 and older, indicating a growing public health concern.
- Both conditions have been increasingly prevalent over the last decade, with forecasts suggesting that dementia cases could nearly triple by 2050, and type 2 diabetes is a known risk factor for cognitive impairment.
- The PHYND trial aims to test the effects of daily phytate supplementation on mild cognitive impairment progression in patients with type 2 diabetes, hypothesizing that phytate may enhance cognitive function and reduce iron buildup in the brain, potentially