Oxidative stress in keratoconus?

Purpose: The purpose of this study was to establish the alterations of oxidative stress-related markers in keratoconus (KC) corneas.

Methods: A total of 6 healthy and 11 ectatic corneas (7 KC and 4 post-LASIK) were studied. Different oxidative stress-related markers were determined to assess their implication in the KC pathophysiology.

Lens opacities in Valencia, Spain.

Purpose: To evaluate the most common lens opacities in Valencia (Spain), analyzed by gender, grade, and type of cataracts. The results are compared with other studies performed at other geographical latitudes and on different races.

Methods: A total of 1951 eyes of patients diagnosed with cataracts, aged between 30 and 96 years, were evaluated in accordance with age, gender, type and degree of the cataract, bilaterality, and symmetry of this disease.

Correlation between optics quality of multifocal intraocular lenses and visual acuity: tolerance to modulation transfer function decay.

Purpose: To study the relationship between the optics quality of multifocal intraocular lenses (IOLs) and distance-corrected near, intermediate, and distance visual acuity to determine the degree to which optics quality must change to produce a significant difference in visual acuity.

Setting: Fundación Oftalmológica del Mediterráneo, Valencia, Spain.

Methods: Monocular distance-corrected visual acuity (decimal and logMAR) was measured at 4 m, 70 cm, and 30 cm under photopic and mesopic conditions in eyes with 1 of 3 multifocal IOL models.

Influence of optic quality on contrast sensitivity and visual acuity in eyes with a rigid or flexible phakic intraocular lens.

Purpose: To determine whether the difference in optic quality between 2 types of phakic intraocular lenses (pIOLs) affects visual quality.

Setting: Fundación Oftalmológica del Mediterráneo, Valencia, Spain.

Methods: Before implantation of a pIOL for myopia, all eyes had an examination including corrected (CDVA) and uncorrected (UDVA) distance visual acuity testing, corneal endothelial cell count (ECC), and intraocular pressure (IOP) measurement.

Foldable Artiflex phakic intraocular lens for the correction of myopia: two-year follow-up results of a prospective European multicenter study.

Objective: To evaluate the safety, efficacy, predictability, stability, and complications of the foldable Artiflex iris-fixated intraocular lens (Ophtec BV, Groningen, The Netherlands) for the correction of myopia in phakic eyes.

Design: Prospective, nonrandomized, open-label, multicenter trial.

Participants: Two hundred ninety eyes of 191 patients aged 18 to 60 years with average spherical equivalent of -7.

Modulation transfer function: rigid versus foldable phakic intraocular lenses.

Purpose: To study in a standard eye model the changes in modulation transfer function (MTF) of a monofocal intraocular lens (IOL) when a phakic IOL (pIOL) is placed in the anterior chamber, compare the MTFs of the rigid Artisan pIOL and foldable Artiflex pIOL, and evaluate the temporal evolution of the MTF of the foldable pIOL after the mechanical stress the pIOL undergoes when injected.

Setting: Fundación Oftalmológica del Mediterráneo, Valencia, Spain.

Methods: The MTF values of the IOLs were calculated from the cross-line spread function recorded with the Opal Vector System.

Image quality with multifocal intraocular lenses and the effect of pupil size: comparison of refractive and hybrid refractive-diffractive designs.

Purpose: To analyze the image quality with a refractive and 2 hybrid refractive-diffractive multifocal intraocular lenses (IOLs) in vitro to determine the IOL modulation transfer function (MTF) following the EN-ISO international standard for distance and near vision and to study the IOLs' behavior with different pupil sizes.

Setting: Fundación Oftalmológica del Mediterráneo, Valencia, Spain.

Methods: This study evaluated 4 IOLs: the hybrid refractive-diffractive AcrySof ReSTOR SN60D3 (Alcon) and Tecnis ZM900 (AMO), the refractive ReZoom NXG (AMO), and the monofocal AcrySof SN60WF (Alcon).

Rate of cataract formation in 343 highly myopic eyes after implantation of three types of phakic intraocular lenses.

Purpose: To assess the feasibility of using phakic intraocular lenses (PIOL) to treat high myopia, and evaluate the incidence of cataract, comparing three different lens types.

Methods: From 1989 to 2002, we implanted three different phakic intraocular lenses (PIOL) in 343 eyes of 232 patients; 231 eyes recieved an Ophtec (Worst-Fechner model, iris-claw), 89 an Adatomed (silicone posterior chamber), and 23 a Staar (posterior chamber, models V2, V3, V4). Average follow-up was 96.

Phakic intraocular lenses to correct high myopia: Adatomed, Staar, and Artisan.

Purpose: To evaluate the feasibility and safety of using phakic intraocular lenses (IOLs) to correct high myopia by comparing 3 IOL models: Adatomed, Staar, and Artisan.

Setting: La Fe University Hospital, Department of Ophthalmology, and the Fundación Oftalmológica del Mediterráneo, Valencia, Spain.

Methods: In this prospective comparative study, a phakic IOL was implanted in 217 highly myopic eyes (118 patients).

Visual performance with multifocal intraocular lenses: mesopic contrast sensitivity under distance and near conditions.

Objective: To evaluate distance and near visual performance under bright (photopic) and dim (mesopic) conditions in patients who had undergone uncomplicated cataract extraction with multifocal or monofocal intraocular lens (IOL) implantation.

Design: Prospective, nonrandomized, masked, comparative, observational case series.

Participants: Thirty-two eyes of 32 patients after zonal-progressive multifocal IOL implantation (Allergan Medical Optics Array SA-40N) and 32 eyes of 32 age-matched patients after monofocal IOL implantation (Allergan Medical Optics SI-40NB).

Mesopic contrast sensitivity function after laser in situ keratomileusis.

Purpose: To evaluate contrast sensitivity under mesopic conditions in patients who have undergone uncomplicated bilateral laser in situ keratomileusis (LASIK) for myopia.

Methods: Best-corrected monocular contrast sensitivity was measured with the Stereo Optical F.A.