Publications by authors named "Jose Julian"

Background: Health Promoting Schools (HPS) have emerged as a powerful framework to promote healthy behaviors in many countries. However, HPS still present several challenges, highlighting the excessive workload involved in the accreditation, design, implementation, and evaluation processes. In this sense, a resource to facilitate the implementation processes may have a positive impact on the support of HPS.

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SUMO conjugation is a conserved process of eukaryotes, and essential in metazoa. Similar to ubiquitylation, a SUMO-activating enzyme links to the SUMO carboxyl-terminal Gly in a thioester bond, and a SUMO-conjugating enzyme accepts activated SUMO and can transfer it to substrates. Unlike ubiquitylation, this transfer can also occur, in an unspecified number of cases, in the absence of ligase-like enzymes.

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Certain E3 ubiquitin ligases play a key role in the abscisic acid (ABA) pathway by targeting clade A type 2C protein phosphatases (PP2Cs) for degradation. At early stages of ABA signaling, degradation of PP2Cs is a complementary step to PP2Cs inhibition by ABA receptors. At later steps, protein levels of PP2Cs are increased as a negative feedback mechanism.

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Article Synopsis
  • Post-translational modifications, especially protein ubiquitylation, are essential for regulating protein function and stability in plants.
  • Ubiquitylation can lead to proteolytic degradation via the 26S proteasome and also influence protein interactions and activities through different chain types.
  • The review specifically explores how ubiquitylation and other modifications of ABA receptors and their coreceptors affect ABA signaling and turnover, highlighting the roles of E3 Ub ligases in this process.
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The identification of those prevalent abscisic acid (ABA) receptors and molecular mechanisms that trigger drought adaptation in crops well adapted to harsh conditions such as date palm (Phoenix dactylifera, Pd) sheds light on plant-environment interactions. We reveal that PdPYL8-like receptors are predominantly expressed under abiotic stress, with Pd27 being the most expressed receptor in date palm. Therefore, subfamily I PdPYL8-like receptors have been selected for ABA signaling during abiotic stress response in this crop.

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Background: School environment provides several intervention opportunities for physical activity. The aim of this study was to examine the relationship between objectively assessed moderate to vigorous physical activity (MVPA) and academic achievement in adolescents.

Methods: Cross-sectional data were collected from 301 students aged between 13 and 15 years (46.

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Unlabelled: This study aimed to investigate the effects of a physical activity intervention, based on self-determination theory and the transtheoretical model, on university students in the contemplation stage.

Participants: 42 students, in the contemplation stage at baseline, were randomly assigned to an experimental group (16 women, 2 men; M age = 19.1 ± 1.

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The turnover of abscisic acid (ABA) signaling core components modulates the plant's response to ABA and is regulated by ubiquitination. We show that Arabidopsis () RING Finger ABA-Related1 (RFA1) and RFA4 E3 ubiquitin ligases, members of the RING between RING fingers (RBR)-type RSL1/RFA family, are key regulators of ABA receptor stability in root and leaf tissues, targeting ABA receptors for degradation in different subcellular locations. RFA1 is localized both in the nucleus and cytosol, whereas RFA4 shows specific nuclear localization and promotes nuclear degradation of ABA receptors.

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The aim of this study was to identify the prevalence and clustering of health-related behaviors in Spanish adolescents and to examine their association with sex, body mass index (BMI), different types of sedentary screen time, and adherence to 24-hour movement guidelines. A final sample of 173 students (M = 12.99 ± 0.

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Grounded in self-determination theory (SDT), prior research has demonstrated that physical education (PE) teachers may have different reasons to engage in teaching. Although some person-centered studies have identified varied motivational profiles in PE teachers, none of these studies have included the three forms of motivation (i.e.

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Early abscisic acid signaling involves degradation of clade A protein phosphatases type 2C (PP2Cs) as a complementary mechanism to PYR/PYL/RCAR-mediated inhibition of PP2C activity. At later steps, ABA induces up-regulation of transcripts and protein levels as a negative feedback mechanism. Therefore, resetting of ABA signaling also requires PP2C degradation to avoid excessive ABA-induced accumulation of PP2Cs.

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Hormone- and stress-induced shuttling of signaling or regulatory proteins is an important cellular mechanism to modulate hormone signaling and cope with abiotic stress. Hormone-induced ubiquitination plays a crucial role to determine the half-life of key negative regulators of hormone signaling. For ABA signaling, the degradation of clade-A PP2Cs, such as PP2CA or ABI1, is a complementary mechanism to PYR/PYL/RCAR-mediated inhibition of PP2C activity.

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Article Synopsis
  • Abscisic acid (ABA) is crucial for regulating root growth and responses to environmental factors like moisture, but the detailed mechanisms behind ABA signaling in roots are still being studied.
  • PYL8, a specific receptor in the PYR/PYL/RCAR family, plays a unique role in root growth regulation and is stabilized by ABA, particularly in the root nuclei, while other similar receptors don't show this response.
  • The research indicates that PYL8 not only acts within its own cells but also can move to surrounding tissues, suggesting a broader interaction in root hormone signaling that helps clarify its important function in regulating root architecture.
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Aims And Objectives: This study aims to establish the outcome of recasting on tensile strength, modulus of elasticity, and hardness of Nickel-chromium alloys.

Materials And Methods: Fifty wax patterns were fabricated, using the lost wax technique, the measurements of which were standardized. They were categorized into five groups of ten each.

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Aims: To determine the influence of hard acrylic denture base materials on the blood flow of mandibular denture supporting mucosa over a period of six months time.

Materials And Methods: Select fifteen edentulous patients of age 55-75 years. The blood flow of the mandibular denture supporting mucosa was measured bilaterally in the molar region and in the incisor region utilizing Ultrasound colour Doppler (2D and Duplex Imaging).

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Context: It has been proposed that Epstein-Barr virus (EBV) plays a role in the etiology of lymphoepithelioma-like carcinoma (LELC) in diverse anatomic locations. In contrast to Asian women, Western women have a low prevalence of LELC of the uterine cervix, and EBV genomes have not been identified.

Objective: To assess the presence of EBV in LELC of the uterine cervix in 4 white Western women.

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