Identification of a Series Containing a Pentafluorophenyl Moiety That Targets Pks13 to Inhibit Growth of .

Although not currently in the infectious disease spotlight, there is still a pressing need for new agents to treat tuberculosis caused by . As there is an ever-increasing amount of clinical resistance to the current drugs, ideally new drugs would be found against novel targets to circumvent pre-existing resistance. A phenotypic growth screen identified a novel singleton, , as an inhibitor of growth.