Usefulness of open data to determine the incidence of COVID-19 and its relationship with atmospheric variables in Spain during the 2020 lockdown.

The SARS-CoV-2 pandemic and the spread of the COVID-19 disease led to a lockdown being imposed in Spain to minimise contagion from 16 March 2020 to 1 May 2020. Over this period, measures were taken to reduce population mobility (a key factor in disease transmission). The scenario thus created enabled us to examine the impact of factors other than mobility (in this case, meteorological conditions) on the incidence of the disease, and thus to identify which environmental variables played the biggest role in the pandemic's evolution.

Quantification and phenotype of regulatory T cells in rheumatoid arthritis according to disease activity score-28.

Here we studied and characterized different peripheral blood (PB) regulatory T cell (Treg) subsets in rheumatoid arthritis (RA) patients and tested the hypothesis that changes in these cells can be linked to the degree of inflammation and relapsing/remission periods. PB cells were examined from RA subjects (n = 60) with different disease activity score-28 (DAS28) and from healthy controls (n = 40). Frequencies of Treg subsets expressing characteristic membrane antigens, FoxP3 or intracellular cytokines were quantified by flow cytometry.