Publications by authors named "Jose Ignacio Martin Gonzalez"
This study aimed to assess the impact of SARS-CoV-2 therapies on the risk of venous thromboembolism (VTE) and other cardiovascular events. A retrospective, multicenter, observational study included hospitalized patients in Spain due to acute SARS-CoV-2 infection from March 2020 to March 2022. A total of 184,324 hospitalized COVID-19 patients were included, with a mean age of 67.
View Article and Find Full Text PDFEffect of intravenous pulses of methylprednisolone 250 mg versus dexamethasone 6 mg in hospitalised adults with severe COVID-19 pneumonia: An open-label randomised trial.
Eur J Clin Invest
January 2023
Background: The efficacy and safety of high versus medium doses of glucocorticoids for the treatment of patients with COVID-19 has shown mixed outcomes in controlled trials and observational studies. We aimed to evaluate the effectiveness of methylprednisolone 250 mg bolus versus dexamethasone 6 mg in patients with severe COVID-19.
Methods: A randomised, open-label, controlled trial was conducted between February and August 2021 at four hospitals in Spain.
Low molecular weight heparin is useful in adult COVID-19 inpatients. Experience during the first Spanish wave: observational study.
Sao Paulo Med J
January 2022
Article Synopsis
- A study in Spain explored how different intensities of anticoagulation, specifically low-molecular-weight heparin (LMWH), impact survival rates in COVID-19 hospitalized patients.
- The research included 690 patients, revealing that those who received any form of LMWH had significantly lower mortality rates compared to those who did not.
- The findings suggest that intermediate-dose LMWH may offer the most benefit, highlighting the need for further randomized controlled trials to investigate optimal anticoagulation strategies for COVID-19 patients.
Background: The use of noninvasive positive pressure ventilation (NPPV) outside the intensive wards has been evaluated in patients with no limitation on life-sustaining support. Our aim was to evaluate its usefulness in general wards for patients with NPPV as the ceiling of ventilator care when admission to the intensive care unit (ICU) has been withheld.
Materials And Methods: Noninvasive positive pressure ventilation was used in 44 patients with acute respiratory failure (ARF) and limitations to respiratory care- 22 with chronic obstructive pulmonary disease (COPD) exacerbations and 22 with acute cardiogenic pulmonary oedema (CPE).