25-Hydroxyivitamin D3 levels in patients with systemic lupus erythematosus and its association with clinical parameters and laboratory tests.

Introduction: The immunoregulatory role of vitamin D has been the object of a growing number of studies in patients with systemic lupus erythematosus (SLE).

Objectives: To determine the serum levels of 25-hydroxyvitamin D3 [25(OH) D] in patients with SLE, and to assess the association of 25(OH)D insufficiency/deficiency with clinical parameters and laboratory tests.

Methods: Cross-sectional, prospective study performed at the SLE Clinic, Department of Rheumatology, Hospital das Clínicas, Universidade Federal de Pernambuco with convenience sampling, including 78 patients with SLE and 64 volunteers (comparison group), matched by gender and age.

Immunological's host profile for HPV and Chlamydia trachomatis, a cervical cancer cofactor.

Over 100 different genotypes of human papillomavirus (HPV) have been isolated to date, while Chlamydia trachomatis is the most common bacterial sexually-transmitted pathogen. This review considers evidence that C. trachomatis infection became a cofactor for HPV establishment and the development of cervical intraepithelial neoplasia.