Publications by authors named "Jose G Valadez-Calderon"

Introduction and objectives Type 2 diabetes mellitus (T2DM) has been one of the main risk factors associated with mortality from the coronavirus disease 2019 (COVID-19). Insulin resistance (IR) is a preceding and underlying condition of T2DM, which has been thought that it could increase mortality from COVID-19 since it favors the entry of severe acute respiratory syndrome coronavirus type 2 in the host cell. This article reports a biochemical study that estimated the prevalence of IR in COVID-19 patients and non-diabetic patients without COVID-19 history.

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Article Synopsis
  • The study investigated the relationship between serum testosterone levels and clinical outcomes in male patients with COVID-19, given the observed higher severity of the disease in this demographic.
  • Among 86 male patients, those who died had significantly lower testosterone levels (4.01 nmol/L) compared to survivors (5.41 nmol/L), indicating that low testosterone may be a risk factor for mortality.
  • Key findings include that testosterone levels below 4.89 nmol/L, along with age over 59 years and high lactate dehydrogenase levels, significantly increase the risk of death from COVID-19 in men.
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Mycetoma is a chronic human infectious disease that produces severe deformation frequently in the lower extremities. Etiological agents include fungi (eumycetoma) and bacteria (actinomycetoma) that produce similar clinical and microscopic changes. The clinical appearance includes swelling, abscesses, ulcers, scars and sinuses that drain purulent material with microbe microcolonies.

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