Publications by authors named "Jose Flavio Affonso de Almeida"

Article Synopsis
  • The study investigates the effectiveness of nonsurgical root canal retreatment (NS-RCRT) using 2% chlorhexidine gel and foraminal enlargement techniques in improving periapical healing and success rates compared to traditional methods.
  • A retrospective analysis of 120 teeth from 80 patients showed a high success rate of 92.5% over an average follow-up of 30 months, with radiographic repair as the main influencing factor.
  • The findings suggest that the new NS-RCRT approach may serve as a viable alternative to tooth extraction, warranting further prospective research to confirm its benefits.
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  • The systematic review investigated how Passive Ultrasonic Irrigation (PUI) affects the healing of periapical tissues in primary root canal treatments compared to conventional syringe irrigation (CSI).
  • The study included randomized clinical trials and analyzed data from 474 patients, finding that PUI resulted in a statistically significant increase in healing rates compared to CSI, with a Relative Risk of 1.10.
  • The review concluded that while there are few high-quality studies, PUI appears to have a beneficial effect on periapical healing in root canal treatments.
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  • The study examined the occurrence of luxation injuries and related dental fractures in patients treated at a Brazilian dental school clinic from 2012 to 2022.
  • Data were collected from 366 clinical records, highlighting that men were more likely to experience luxation injuries than women, with extrusive luxation being the most common type.
  • Results indicated that patients with luxation injuries sought care more quickly and had a higher likelihood of needing endodontic treatment, particularly for injuries resulting from traffic accidents, though luxation combined with fractures did not increase treatment needs.
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Article Synopsis
  • Persistent apical periodontitis post-root canal treatment may require surgical intervention when non-surgical methods fail, and endodontic microsurgery (EMS) is utilized to address complex cases.
  • A 60-year-old male underwent unsuccessful non-surgical retreatment and was treated surgically with photodynamic therapy (PDT) using a curcumin-based photosensitizer, resulting in complete recovery after one year.
  • The combination of EMS and PDT showed promise in enhancing healing and reducing microorganisms, suggesting further research is needed to establish this treatment as a standard practice.
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Introduction: This retrospective cohort study aimed to estimate the success rate (SR) of primary root canal treatment on teeth with a diagnosis of pulp necrosis (PN) and asymptomatic apical periodontitis (AAP) when using 2% chlorhexidine gel as an auxiliary chemical substance and foraminal enlargement instrumentation technique.

Methods: This study evaluated 178 patients with 206 teeth submitted to primary root canal treatment performed by graduate residents in endodontics. The inclusion criteria were patients who underwent treatment over a period of 1-7 years on teeth with a diagnosis of PN and AAP.

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Background: A smile is considered one of the most important soft skills in social interaction. And discolored teeth may effect this. It is known that some photosensitizer agents (PS) used in photodynamic therapy (PDT) during root canal treatment could play a significant role in tooth color change, and thus the main objective of this systematic review is to address whether performing PDT can influence tooth color change and to synthesize the most effective methods to remove PS from the root canal system.

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Background: Dental caries is the most common oral disease worldwide, and it is estimated to affect 2.3 billion people, with at least 530 million of them being schoolchildren with decayed primary teeth. This condition can rapidly evolve into irreversible pulp inflammation and pulp necrosis and thus requiring endodontic intervention.

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Background: Photodynamic therapy (PDT) is an adjunctive treatment that aims to inactivate microorganisms through an oxidative reaction produced by irradiating a photosensitizing agent. The quest for improved root canal disinfection has sought supplementary methods when performing chemomechanical procedures. From this perspective, PDT protocols were proposed as an auxiliary approach in endodontics.

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This study aimed to investigate the prevalence of dental trauma in Brazilian children and adolescents. A systematic review was conducted considering eight databases: MEDLINE (via PubMed), LILACS, BBO, Scopus, Embase, Web of Science, Open Access Theses and Dissertations, and OpenThesis. Only prevalence studies that used a probabilistic sampling method were included, without restriction on year or language of publication.

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Background/aim: Dental trauma (DT) occurs frequently in children and adolescents. Therefore, understanding the factors associated with its occurrence in these age groups is important to establish specific preventive measures. The aim of this study was to investigate the relationships of lip coverage, overjet, and open bite to dental trauma in Brazilian children and adolescents.

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Objective: The present clinical study investigated the microbiota of teeth with persistent secondary endodontic infection in the different phases of root canal retreatment.

Methods: Twenty filled single-rooted teeth with apical periodontitis were included. Samples were collected with sterile paper points before chemo-mechanical preparation (CMP) (S1), after CMP (S2) and after 30 days of calcium hydroxide-based intracanal medication (ICM) (S3).

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This study compares the clinical success rate and continued radiographic root development of apexification and regenerative endodontic procedure in traumatised immature permanent teeth, and proposes a method to evaluate apical convergence, namely apical angle. Clinical and radiological data were collected from 44 treated teeth (22 with apexification and 22 with regenerative endodontic procedure). The preoperative and follow-up periapical radiographs were analysed to calculate the percentage changes in root length, root width, apical diameter and apical angle.

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Objective: Pulp revascularization is an effective treatment for immature necrotic teeth. Calcium hydroxide has been used in pulp revascularization as an intracanal medication due to its antimicrobial action and the non-exhibition of crown discoloration and cytotoxicity for stem cells from the apical papilla. Our study aimed to investigate the clinical success and quantitative radiographic changes of root development in immature traumatized teeth using calcium hydroxide plus 2% chlorhexidine gel as intracanal medication.

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Objectives: The purpose of the present study was to evaluate the effect of calcium hydroxide with 2% chlorhexidine gel (HCX) or distilled water (HCA) compared to triple antibiotic paste (TAP) on push-out bond strength and the cement/dentin interface in canals sealed with White MTA Angelus (WMTA) or Biodentine (BD).

Materials And Methods: A total of 70 extracted human lower premolars were endodontically prepared and randomly divided into 4 groups according to the intracanal medication, as follows: group 1, HCX; group 2, TAP; group 3, HCA; and group 4, control (without intracanal medication). After 7 days, the medications were removed and the cervical third of the specimens was sectioned into five 1-mm sections.

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Objective: The objective of this work was to investigate in vivo the effects of calcium hydroxide-based intracanal medication (ICM) on the levels of bacteria, pro-inflammatory cytokines (PICs), and matrix metalloproteinases (MMPs) in root canals and periradicular tissues of teeth with failure of the root canal treatment and apical periodontitis.

Materials And Methods: Twenty infected root canals of single-rooted teeth were randomly assigned into two groups according to the irrigant used for chemomechanical preparation (CMP) (n = 10 per group): G1 - 2% chlorhexidine (CHX) gel and G2 - 6% sodium hypochlorite (NaOCl). Root canal contents were taken by using paper points before CMP (S1) and after 30 days of calcium hydroxide-based ICM (S2).

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Article Synopsis
  • * Researchers created dentin specimens from human teeth and divided them into four groups based on their drying methods: vacuum only, paper points, and two ethanol treatments (70% and 100%).
  • * Results showed that 70% and 100% ethanol significantly improved the smoothness and wettability of the dentin surface, leading to better interaction with the AH Plus sealer compared to other drying methods.
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Intrusive luxation is a severe trauma-related event with a high frequency of pulp necrosis and root resorption. A common complication following intrusion is tooth ankylosis, which can extend to progressive replacement root resorption. An increasing infraposition in growing individuals can also occur.

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This clinical study aimed to evaluate the relationship of the delay between dental trauma and the initial attendance to the development of external inflammatory root resorption in permanent teeth affected by severe luxation. Sixty-seven patients, aged between 11 and 56 years, presenting 133 injured teeth with closed apex (56 extrusive luxation, 69 lateral luxation and 8 intrusive luxation) were followed up for a minimum of 24 months. The time elapsed between dental trauma and the initial attendance was recorded.

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Aim: The aim of this study was to investigate the influence of cleaning methods to remove zinc oxide-eugenol-based root canal sealer (Endomethasone) on the bond strength of the self-etching adhesive to dentin.

Materials And Methods: Twenty crowns of bovine incisors were cut to expose the pulp chamber. A zinc oxide- and eugenol-based sealer was placed for 10 min in contact with the pulp chamber dentin.

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Introduction: The aim of this study was to evaluate the efficacy of sodium thiosulfate (Na2S2O3) for restoring adhesion to pulp chamber dentin treated with sodium hypochlorite (NaOCl) and EDTA.

Methods: Sixty-three crowns of bovine incisors were cut to expose the dentin pulp chamber. The specimens were polished and randomly distributed into 9 groups (n = 7) according to the following protocols used: 0.

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Unlabelled: Phosphoric acid has been suggested as an irrigant due to its effectiveness in removing the smear layer.

Objectives: The purpose of this study was to compare the antimicrobial and cytotoxic effects of a 37% phosphoric acid solution to other irrigants commonly used in endodontics.

Material And Methods: The substances 37% phosphoric acid, 17% EDTA, 10% citric acid, 2% chlorhexidine (solution and gel), and 5.

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Introduction: Pulp revascularization may be considered a promising alternative for necrotic immature teeth. Many studies have accomplished passive decontamination associated with an antibiotic paste. To date, there is no report evaluating calcium hydroxide associated with 2% chlorhexidine gel for revascularization therapy.

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Introduction: Stem cells of the apical papilla (SCAP) have been identified as an important population of mesenchymal stem cells (MSCs) in regenerative endodontics. Preclinical studies that evaluate the various aspects of the regenerative process must use fully characterized MSCs. The phenotype of these cells when maintained in culture is crucial for the translational applicability of these studies.

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Dental trauma generally requires multidisciplinary planning and treatment for good prognosis. When immature teeth are traumatized to a degree where pulp necrosis ensues, the objective of root canal treatment should be apexogenesis and root maturation. Apexification of the root is the conventional choice, which involves cleaning the canal and filling it with a temporary medication that stimulates the formation of a calcific apical barrier.

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Introduction: The aim of this study was to investigate the effects of pretreatment of gel chlorhexidine (CHX) and ethanol (EtOH) on the bond strength and durability of the adhesion of the fiber post relined with resin composite to the root dentin using a total etch adhesive system.

Methods: Forty bovine incisor roots were divided into four groups after phosphoric acid etching: irrigation with physiologic solution (control), 5 minutes with CHX, 1 minute with EtOH, and 5 minutes with chlorhexidine followed by 1 minute with EtOH. Fiber posts relined with resin composite were cemented with either RelyX ARC (3M ESPE, St Paul, MN) and a total etch adhesive system Scotchbond Multi-Purpose (3M ESPE).

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