Systematic literature review: influence of low-level laser on orthodontic movement and pain control in humans.

Objective: The purpose of this study was to systematically review the literature to check the influence of low-level laser (LLL) on orthodontic movement and pain control in humans, and what dose ranges are effective for pain control and increased speed of orthodontic movement.

Methods: Computerized and manual searches were conducted up to January 4, 2014 for clinical studies that addressed these objectives. The selection criteria required that these studies (1) be prospective controlled clinical trials (CCT) and randomized clinical trials (RCT); (2) only use LLL in both infrared and visible red wavelengths, a laser with emission of constant wave; (3) have all main parameters of dose described, or at least conditions for calculation of the energy, in Joules; and (4) be published in Portuguese, English, or Spanish and be meta-analyses.