Publications by authors named "Jose Clemente Ibarra Ponce de Leon"

The transfer of technology from health research institutions to businesses that develop new medical treatments has generated great benefits for public health at a global level. Mexico however, is lagging in innovation indicators. There are important cultural, regulatory, and financial barriers that limit innovation in Mexico.

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Today, regenerative medicine requires new sources of multipotent stem cells for their differentiation to chondrocytes using the mediums of differentiation available in the market. This study aimed to determine whether the Mesenchymal Stem Cells (MSCs) isolated from Mobilized Peripheral Blood (MPB) in sheep using the Granulocyte Colony-Stimulating Factor (G-CSF), have the ability of first acquire a fibroblast-like morphology after being forced out of the bone marrow niche by G-CSF and second, if the cells have the capacity to express collagen type-II α I in primary culture using a human commercial media of differentiation. Six Suffolk male sheep with age of 2 years were mobilized using G-CSF.

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Article Synopsis
  • The study compares the repair quality of chondrocytes in a three-dimensional co-culture system using samples from cadaveric and live donors.
  • It evaluates the histological quality of newly-formed tissue, finding co-cultured constructs perform significantly better than non-co-cultured in key metrics like glycosaminoglycan content.
  • The research indicates viable chondrocytes can be successfully isolated from cadaveric donors shortly after death, and cryopreservation doesn’t diminish their ability to generate cartilage-like tissue.
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Osteosarcoma is the most common primary high-grade bone tumor in both adolescents and children. Early tumor detection is key to ensuring effective treatment. Serum marker discovery and validation for pediatric osteosarcoma has accelerated in recent years, coincident with an evolving understanding of molecules and their complex interactions, and the compelling need for improved pediatric osteosarcoma outcome measures in clinical trials.

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Introduction: Arthroscopic repair of the rotator cuff have shown have shown encouraging clinical results. However, few authors have assessed integrity of repair with ultrasound. The presence of re-rupture by ultrasonography in a rotator cuff repair may not relate to the patient's functional status.

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Unlabelled: Symptomatic Os trigonum requires an initial conservative treatment, if clinical improvement cannot be obtained, then surgical treatment is performed with a traditional open approach. We describe an endoscopic technique: with the patient on prone position two portals are made, the first is posterolateral just at the tip of the fibula just lateral to the Achilles tendon; the second portal is posteromedial and at the same level to the first one but medial to the Achilles tendon. With the use of this technique, a wide and safe working field is obtained for the resection of the Os trigonum.

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Objective: To analyze the subjective and objective outcome of arthroscopic meniscal repair in patients with chronic meniscal lesions.

Methods: A group of patients that underwent arthroscopic meniscal repair of chronic tears with a minimum follow-up of six months was retrospectively evaluated. Physical examination oriented at finding persistent meniscal lesions was performed.

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Quadriceps tendon (QT) is becoming a popular graft for primary and revision ligament surgery. A subcutaneous technique for graft harvesting a QT is presented. Special closed tendon strippers were designed; these devices have 10- and 11-mm inner diameters and are stronger and sharper than regular hamstrings strippers.

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