Reduced precipitation can induce ecosystem regime shifts in lakes by increasing internal nutrient recycling.

Eutrophication is a main threat to continental aquatic ecosystems. Prevention and amelioration actions have been taken under the assumption of a stable climate, which needs reconsideration. Here, we show that reduced precipitation can bring a lake ecosystem to a more productive regime even with a decline in nutrient external load.

Promoting psychological health in women with SCI: Development of an online self-esteem intervention.

Background: There are no known interventions addressing self-esteem in women following spinal cord injury (SCI).

Objectives: To test the feasibility of an online self-esteem intervention for women with disabilities, as modified for women with SCI.

Method: We conducted a randomized, controlled feasibility test of a self-esteem intervention (N = 21).

Radioembolization of Hepatocellular Carcinoma with Built-In Dosimetry: First Results with Uniformly-Sized, Biodegradable Microspheres Labeled with Re.

A common form of treatment for patients with hepatocellular carcinoma (HCC) is transarterial radioembolization (TARE) with non-degradable glass or resin microspheres (MS) labeled with Y (Y-MS). To further simplify the dosimetry calculations in the clinical setting, to have more control over the particle size and to change the permanent embolization to a temporary one, we developed uniformly-sized, biodegradable Re-labeled MS (Re-MS) as a new and easily imageable TARE agent. MS made of poly(-lactic acid) were produced in a flow focusing microchip.

Tracking climate change in oligotrophic mountain lakes: Recent hydrology and productivity synergies in Lago de Sanabria (NW Iberian Peninsula).

Mountain lakes are particularly sensitive to global change as their oligotrophic conditions may be rapidly altered after reaching an ecological threshold, due to increasing human impact and climate change. Sanabria Lake, the largest mountain lake in the Iberian Peninsula and with a recent history of increased human impact in its watershed, provides an opportunity to investigate recent trends in an oligotrophic, hydrologically-open mountain lake, and their relationship with climate, hydrological variability and human pressure. We conducted the first systematic and detailed survey of stable isotope compositions of Sanabria Lake and Tera River together with limnological analyses during 2009-2011.

Utilization of nanoparticles as X-ray contrast agents for diagnostic imaging applications.

Among all the diagnostic imaging modalities, X-ray imaging techniques are the most commonly used owing to their high resolution and low cost. The improvement of these techniques relies heavily on the development of novel X-ray contrast agents, which are molecules that enhance the visibility of internal structures within the body in X-ray imaging. To date, clinically used X-ray contrast agents consist mainly of small iodinated molecules that might cause severe adverse effects (e.

Uniform polymer microspheres: monodispersity criteria, methods of formation and applications.

For many applications, polymer microspheres (MS) should possess a monodisperse size distribution. With such uniformity they are able to deliver precise amounts of drug per MS, optimize the release kinetics of an encapsulated drug, obtain repeatable in vivo biodistributions to different organs and tissues, and obtain the maximum protection of (protein) drugs from degradation. This review classifies monodisperse polymer MS according to their methods of production and gives examples of the formation of uniform MS and their applications in the medical field.