Publications by authors named "Jose C Fernandez-Ferro"
Background And Purpose: Reperfusion therapy is the standard of care for ischaemic stroke; however, there is a need to identify new therapeutic targets able to ameliorate cerebral damage. Neutrophil β adrenoceptors (β1AR) have been linked to neutrophil migration during exacerbated inflammation. Given the central role of neutrophils in cerebral damage during stroke, we hypothesize that β1AR blockade will improve stroke outcomes.
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- Recent studies showed a rise in cerebral venous thrombosis (CVT) cases during the COVID-19 pandemic, prompting this evaluation of hospitalization and mortality rates comparing the pandemic year (2020) to the year prior (2019).
- A cross-sectional study analyzed data from 171 stroke centers worldwide, focusing on CVT admissions and associated mortality from January 2019 to May 2021, revealing no significant differences in overall CVT volume or mortality between 2019 and 2020.
- However, the first five months of 2021 saw a notable increase in CVT admissions compared to 2019 and 2020, with higher mortality rates linked to COVID-19-positive patients and instances of vaccine-induced immune