Bowel-Associated Dermatosis-Arthritis Syndrome: A Report of a Rare Case.

A 31-year-old female, recently discharged after improvement of an exacerbation of ulcerative colitis, returned to the hospital due to fever, polyarthralgia affecting the knees and ankles, and symmetric violaceous papulopustular lesions on her arms, trunk, and lower limbs. Histological examination revealed superficial dermal edema and perivascular invasion of neutrophils with leukocytoclasia, consistent with neutrophilic dermatosis, and a diagnosis of bowel-associated dermatosis-arthritis syndrome (BADAS) was established. BADAS is a rare, characteristic neutrophilic dermatosis and arthritis mainly associated with intestinal inflammatory disease due to bacterial overgrowthand subsequent immune complex formation and deposition.

Chemotherapy-Induced Cutaneous Sclerosis: A Rare Clinical Finding.

Scleroderma-like cutaneous sclerosis has been reported as a rare adverse reaction to several drugs, including the chemotherapeutical agent paclitaxel, used in therapeutic regimens for several malignancies. The sclerosis is usually limited to the skin, most commonly presenting in the lower limbs after weeks to months of therapy but is often refractory to treatment and progresses even after discontinuation of the offending agents, with significant resulting morbidity. We report a rare case of severe cutaneous sclerosis secondary to chemotherapy with nab-paclitaxel and gemcitabine, which did not respond to treatment and led to discontinuation of chemotherapy.

Differential diagnosis between urticarial vasculitis and chronic spontaneous urticaria: An international Delphi survey.

Background: Urticarial vasculitis (UV) should be differentiated from chronic spontaneous urticaria (CSU) in patients initially presenting with recurrent wheals, although criteria for differential diagnosis remain ill-defined.

Objectives: To set the goals, define criteria and unmet needs in UV diagnosis and differential diagnosis with CSU, and explore the possibility of coexistence of both diseases.

Methods: Thirteen experts experienced in UV research participated in a Delphi survey of European Academy of Allergy and Clinical Immunology taskforce.

Basal Cell Carcinomas After Radiotherapy Show More Frequent Follicular Differentiation Than Tumors From Sun-Exposed Areas: Immunohistochemical Study With a Special Focus on Infundibulocystic Basal Cell Carcinoma.

Patients submitted to radiotherapy for tinea capitis in childhood have an increased incidence of scalp basal cell carcinomas (BCCs) but also of other neoplasms, namely, follicular tumors. In a cohort of such patients, we also found a high incidence of infundibulocystic BCCs, an otherwise rare variant. We thus hypothesized that postradiotherapy BCCs could be more prone to display follicular differentiation.

Basal cell carcinomas of the scalp after radiotherapy for tinea capitis: Clinicopathological study in a case series of 96 patients with analysis of 427 tumours.

Background/objectives: Low-dose X-ray radiotherapy to treat tinea capitis during childhood is a well-known risk factor for scalp basal cell carcinomas (BCCs). Post-radiotherapy BCCs are often multiple, and it has been suggested that they display more aggressive features. Our main objective was to study the clinicopathological aspects of post-radiotherapy BCCs to evaluate their biological behaviour and identify features that may differ from other BCCs.