High percentage of immune Th1 and Tc1 cells infiltrating visceral adipose tissue in people with obesity.

Subcutaneous (SAT) and visceral (VAT) adipose tissue dysfunction during the obesity onset can lead to increased expression of inflammatory molecules, and consequently to immune cell infiltration. The aim was to deeply characterize the T cells, those infiltrating SAT and VAT, compared to peripheral blood (PB), in individuals undergoing bariatric surgery. Forty-two adult individuals were recruited, SAT and VAT samples were collected.

Synthesis and Biological Evaluation of Novel 2-imino-4-thiazolidinones as Potential Antitumor Agents for Glioblastoma.

Aims: The purpose of our study was to explore the molecular hybridization between 2- imino-4-thizolidione and piridinic scaffolds and its potential antitumor activity.

Background: Glioblastoma is the most aggressive glioma tumor clinically diagnosed malignant and highly recurrent primary brain tumor type. The standard of treatment for a glioblastoma is surgery, followed by radiation and chemotherapy using temozolomide.

Bodyweight distribution between limbs, muscle strength, and proprioception in traumatic transtibial amputees: a cross-sectional study.

Objectives: To evaluate how transtibial amputation (TT) affects bodyweight distribution, voluntary knee joint position sense (JPS), and quadriceps (QUA) and hamstrings (HAM) strength in prosthetized patients.

Methods: Only TT patients who had been prosthetized for more than one year were included, and an age-paired able-bodied group was used as control. The participants stood on force plates with their eyes open to measure bodyweight distribution between the limbs.

Development and Validation of a Descriptive Cognitive Model for Predicting Usability Issues in a Low-Code Development Platform.

Objective: The aim of the study was the development and evaluation of a Descriptive Cognitive Model (DCM) for the identification of three types of usability issues in a low-code development platform (LCDP).

Background: LCDPs raise the level of abstraction of software development by freeing end-users from implementation details. An effective LCDP requires an understanding of how its users conceptualize programming.

Ruptured Hemorrhagic Hepatic Cyst: An Unusual Case Report.

Background: Hemorrhagic rupture of a hepatic cyst is rare. To date, very few cases have been reported in the literature.

Case Report: A patient with a history of a suspected liver hydatid cyst presented to the emergency department with abdominal pain and fever.

Ovicidal in vitro activity of 2-aryl-3-(2-morpholinoethyl)thiazolidin-4-ones and 2-aryl-3-(3-morpholinopropyl)thiazolidin-4-ones against Fasciola hepatica (Linnaeus, 1758).

Although there is a variety of biological activity reports regarding compounds derived from thiazolidin-4-ones, no data related to ovicidal activity against trematodes, particularly Fasciola hepatica are available. Since there are reports about anthelmintic resistance in F. hepatica, new drugs are required.

Depth cues and perceived audiovisual synchrony of biological motion.

Background: Due to their different propagation times, visual and auditory signals from external events arrive at the human sensory receptors with a disparate delay. This delay consistently varies with distance, but, despite such variability, most events are perceived as synchronic. There is, however, contradictory data and claims regarding the existence of compensatory mechanisms for distance in simultaneity judgments.

A literature review about usability evaluation methods for e-learning platforms.

The usability analysis of information systems has been the target of several research studies over the past thirty years. These studies have highlighted a great diversity of points of view, including researchers from different scientific areas such as Ergonomics, Computer Science, Design and Education. Within the domain of information ergonomics, the study of tools and methods used for usability evaluation dedicated to E-learning presents evidence that there is a continuous and dynamic evolution of E-learning systems, in many different contexts -academics and corporative.

Holographic stress analysis in a distal extension removable partial denture.

This study examines stress analysis of the mandible when submitted to mastication simulated forces over a distal extension removable partial denture. Two situations were analyzed upon loading: small pins had been placed over the bone crest and under the denture; low amplitude loads were applied over tooth 34-37. Holographic interferometry techniques were used to assess mandible's deformation.