Publications by authors named "Jose Bras Cachinho"

Article Synopsis
  • A study was conducted at Tours University Hospital to investigate an outbreak of linezolid-resistant strains of bacteria (LRSE) from 2017 to 2021, focusing on their resistance mechanisms and transmission routes.
  • Out of 34 LRSE isolates, 20 were analyzed, revealing high resistance to linezolid linked to a specific genetic mutation, with most strains being closely genetically related (95% similarity).
  • The findings suggest that prior use of linezolid may have contributed to the outbreak, and hand-to-hand transmission by healthcare workers could have played a role; the study also evaluated a new typing method, IR-Biotyper, which showed promise for future use.
View Article and Find Full Text PDF

Patients infected with severe acute respiratory syndrome coronavirus 2 might have bacterial and fungal superinfections develop. We describe a clinical case of coronavirus disease with pulmonary aspergillosis associated with Bordetella hinzii pneumonia in an immunocompetent patient in France. B.

View Article and Find Full Text PDF

Mycoplasma genitalium is an emerging agent of sexually transmitted infections, associated with urethritis, cervicitis, and pelvic inflammatory disease. Over the past decade, a remarkable increase in macrolide-resistant M. genitalium, the first-line treatment, is observed all over the world.

View Article and Find Full Text PDF

French recommendations for the screening of hepatitis B virus (HBV) infection were updated in 2019 with the association of three markers: HBs Ag, anti-HBs Ab and anti-HBc Ab. These three markers allow identification of infected patients, vaccinated patients and patients who have been in contact with HBV. A positive HBs Ag is usually associated with HBV infection but this interpretation must take into account the clinical context.

View Article and Find Full Text PDF

Background: Currently, the biological diagnosis of Pneumocystis jirovecii pneumonia (PjP infection) usually relies on microbiological investigations in bronchial-alveolar lavage fluid (BALF) by conventional staining methods and/or molecular biology. However, bronchial-alveolar lavage is sometimes complicated to manage, especially in weakened patients. Therefore, alternative clinical samples-easier to collect-are warranted in such specific contexts.

View Article and Find Full Text PDF