Publications by authors named "Jose Barbas Del Buey"
The effectiveness of nirsevimab in reducing the burden of disease due to respiratory syncytial virus (RSV) infection over time in the Madrid region (Spain): a prospective population-based cohort study.
Front Public Health
September 2024
Article Synopsis
- Respiratory syncytial virus (RSV) is a significant cause of illness and death among children under 5, prompting a study on the effectiveness of nirsevimab, a long-acting monoclonal antibody, for preventing respiratory issues over time.
- A cohort study involving infants in the Madrid region revealed that nirsevimab significantly reduced the risk of hospitalization due to RSV, showing effectiveness rates of 93.6% at 30 days and 87.6% at 150 days.
- The findings indicate that while nirsevimab is highly effective in preventing severe RSV cases, its protective effects diminish over time, though it remains effective at preventing hospital admissions even after several months.
Background: With more than 7500 cases reported since April 2022, Spain has experienced the highest incidence of mpox in Europe. From 12 July onward, the modified vaccinia Ankara-Bavaria Nordic (MVA-BN) smallpox vaccine was offered as pre-exposure prophylaxis for those receiving pre-exposure prophylaxis for human immunodeficiency virus (HIV-PrEP). Our aim was to assess the effectiveness of 1 dose of MVA-BN vaccine as pre-exposure prophylaxis against mpox virus (MPXV) infection in persons on HIV-PrEP.
View Article and Find Full Text PDFBackgroundAppropriate vaccination strategies have been key to controlling the outbreak of mpox outside endemic areas in 2022, yet few studies have provided information on mpox vaccine effectiveness (VE).AimTo assess VE after one dose of a third-generation smallpox vaccine against mpox when given as post-exposure prophylaxis (PEP) within 14 days.MethodsA survival analysis in a prospective cohort of close contacts of laboratory-confirmed mpox cases was conducted from the beginning of the outbreak in the region of Madrid in May 2022.
View Article and Find Full Text PDFObjective: Tuberculosis is a major public health problem and most cases are concentrated in vulnerable populations. The objective was to describe the incidence rates trend in native and foreign population (2009-2018) in Madrid Region.
Methods: Retrospective analysis of cases from the Tuberculosis Regional Registry of cases of Madrid Region 2009-2018.
[Daily Surveillance of Pandemic Influenza (H1N1) 2009 by primary care electronic clinical records in the Madrid region].
Rev Esp Salud Publica
February 2011
Background: Pandemic influenza (H1N1) 2009 led to implementation in the Madrid Region of new strategies of epidemiology surveillance in order to give response to the need of immediacy and exhaustiveness.
Methods: Descriptive cross-sectional study between May 1th 2009 and May 22th 2010. All disease episodes registered and reported as influenza disease were collected every day from electronic clinical records in primary care of Madrid Regional Public Health System.