Publications by authors named "Jose Augusto Barreto-Filho"
New coronavirus SARS-CoV-2 (COVID-19) has caused chaos in health care systems. Clinical manifestations of COVID-19 are variable, with a complex pathophysiology and as yet no specific treatment. It has been suggested that the renin-angiotensin-aldosterone system has a possible role in the severity of cases and the number of deaths.
View Article and Find Full Text PDFDisparities in Access and Mortality of Patients With ST-Segment-Elevation Myocardial Infarction Using the Brazilian Public Healthcare System: VICTIM Register.
J Am Heart Assoc
October 2019
Background There is a scarcity of knowledge as to whether rates of myocardial reperfusion use and 30-day mortality for patients with ST-segment-elevation myocardial infarction are similar among patients using the Brazilian Public Health System (SUS) and those using the private healthcare system. Methods and Results A total of 707 patients were analyzed using the VICTIM (Via Crucis for the Treatment of Myocardial Infarction) register database; 589 patients from the SUS and 118 from the private network with ST-segment-elevation myocardial infarction, who attended hospitals with the capacity to perform primary percutaneous coronary intervention (PCI) were investigated. The timeline, rates of use of PCI, and the 30-day probability of death were investigated, comparing the SUS patients to those in the private system.
View Article and Find Full Text PDFObjectives: To evaluate the effects of aging, gender and body mass index on the heart rate variability (HRV), and to compare the patterns of global autonomic regulation (GAR) and parasympathetic outflow (PO) throughout the aging process.
Design, Setting And Participants: CROSS-SECTIONAL: Large sample of community-based adults and elderly people. Individuals aged from 40 to 100 years, functionally independent and with satisfactory cognitive function defined as the self-capacity to interact with an interviewer (N= 1743).
Importance: It is unknown whether hospital transfer rates for patients with acute myocardial infarction admitted to nonprocedure hospitals (facilities that do not provide catheterization) vary and whether these rates further influence revascularization rates, length of stay, and mortality.
Objectives: To examine hospital differences in transfer rates for elderly patients with acute myocardial infarction across nonprocedure hospitals and to determine whether these rates are associated with revascularization rates, length of stay, and mortality.
Design, Setting, And Participants: We used Medicare claims data from January 1, 2006, to December 31, 2008, to assess transfer rates in nonprocedure hospitals, stratified according to transfer rates as low (≤ 20%), mid-low (>20%-30%), mid-high (>30%-40%), or high (>40%).
Objectives: To determine whether high performing hospitals with low 30 day risk standardized readmission rates have a lower proportion of readmissions from specific diagnoses and time periods after admission or instead have a similar distribution of readmission diagnoses and timing to lower performing institutions.
Design: Retrospective cohort study.
Setting: Medicare beneficiaries in the United States.
Importance: There is a need to describe contemporary outcomes of surgical aortic valve replacement (AVR) as the population ages and transcatheter options emerge.
Objective: To assess procedure rates and outcomes of surgical AVR over time.
Design, Setting, And Participants: A serial cross-sectional cohort study of 82,755,924 Medicare fee-for-service beneficiaries undergoing AVR in the United States between 1999 and 2011.
Background: The Mean Heart Rate (MHR) tends to decrease with age. When adjusted for gender and diseases, the magnitude of this effect is unclear.
Objectives: To analyze the MHR in a stratified sample of active and functionally independent individuals.
Article Synopsis
- The study investigates the effectiveness of stress echocardiography (SE) for predicting all-cause mortality and major cardiac events (MACE) in patients with intermediate risk for coronary artery disease (CAD) who had normal exercise tests (ET).
- Out of 397 patients analyzed, those with positive SE indicating myocardial ischemia had a significantly higher risk of MACE, making SE a useful tool for identifying higher-risk patients.
- Key independent predictors for all-cause mortality included being male and over 60 years of age, highlighting the need for targeted monitoring in these groups even with normal ET results.
Background: Chronotropic incompetence (CI), defined as failure to achieve less than 80% of age-expected heart rate, is a predictor of mortality and adverse cardiovascular events and may confer a worse prognosis in elderly diabetic individuals.
Objective: To evaluate the prognostic value of chronotropic incompetence (CI) in elderly diabetic patients considering endpoints with acute myocardial infarction (AMI), cerebrovascular disease (CVD) and overall mortality and compare clinical and echocardiographic characteristics between patients with and without CI.
Method: A total of 298 elderly diabetic patients undergoing exercise echocardiography (EE) were studied from January 2001 to December 2010.
Importance: To better guide strategies intended to reduce high rates of 30-day readmission after hospitalization for heart failure (HF), acute myocardial infarction (MI), or pneumonia, further information is needed about readmission diagnoses, readmission timing, and the relationship of both to patient age, sex, and race.
Objective: To examine readmission diagnoses and timing among Medicare beneficiaries readmitted within 30 days after hospitalization for HF, acute MI, or pneumonia.
Design, Setting, And Patients: We analyzed 2007-2009 Medicare fee-for-service claims data to identify patterns of 30-day readmission by patient demographic characteristics and time after hospitalization for HF, acute MI, or pneumonia.
Reducing the cardiovascular disease burden: justified means for getting to the end.
Circ Cardiovasc Qual Outcomes
July 2012
Metabolic syndrome has been proposed as a predictor of cardiovascular risk. However, such idea lacks strong scientific basis. This article reviews the evidence regarding that issue, challenging the existing paradigm of the prognostic value of metabolic syndrome.
View Article and Find Full Text PDFBackground: Non-adherence to treatment is an important and often unrecognized risk factor that contributes to reduced control of blood pressure (BP).
Objective: To determine the association between treatment adherence measured by a validated version in Portuguese of the 8-item Morisky Medication Adherence Scale (MMAS-8) and BP control in hypertensive outpatients.
Methods: A cross-sectional study was carried out with hypertensive patients older than 18 years, treated at six of the Family Health Strategy Units in Maceió (AL), through interviews and home blood pressure measurements, between January and April 2011.
Outcomes for mitral valve surgery among Medicare fee-for-service beneficiaries, 1999 to 2008.
Circ Cardiovasc Qual Outcomes
May 2012
Background: Mitral valve surgery in older adults carries with it substantial morbidity and mortality risks, yet there are a paucity of national surveillance data. Therefore, we sought to determine trends in hospitalization rate, readmission, and mortality among Medicare fee-for-service (FFS) patients undergoing mitral valve surgery.
Methods And Results: Inpatient Medicare standard analytic files were used to identify 100% of FFS patients aged ≥ 65 years who underwent mitral valve surgery between 1999 and 2008.
Clinical and echocardiographic parameters associated with low chronotropic index in non-elderly patients.
Arq Bras Cardiol
May 2012
Article Synopsis
- Chronotropic incompetence (CI) is often overlooked in cardiac assessments, despite evidence linking it to higher morbidity and mortality.
- A study involving 1,798 non-elderly patients undergoing stress echocardiography found that 15% had CI, which correlated with various clinical and echocardiographic indicators of heart failure (HF).
- Key findings indicated that factors like dyspnea, chest pain history, and increased left ventricular mass were linked to HF, while CI itself did not raise the likelihood of myocardial ischemia in these patients.
Background: Obesity is a chronic and multifactorial disease, associated with increased cardiovascular risk, especially diastolic heart failure.
Objective: To evaluate left ventricular diastolic function in morbidly obese patients in the pre-operative for bariatric surgery, correlating it with cardiovascular risk factors and heart structure.
Methods: This is a cross-sectional study with 132 patients eligible for bariatric surgery submitted to transthoracic echocardiography assessment and of cardiovascular risk factors, as follows: 97 women (73.
Prognostic value of exercise stress echocardiography in patients with left bundle branch block.
Arq Bras Cardiol
December 2011
Background: The literature lacks studies about the prognostic value of exercise stress echocardiography (ESE) in patients with complete left bundle branch block (LBBB) of the bundle of His.
Objective: To assess the prognostic value of ESE in patients with LBBB.
Methods: This is a retrospective cohort that evaluated 135 patients with LBBB, from January 2001 to October 2009, of which 37.