Olfactory disorders have a significant impact on patients' quality of life but are often underestimated in clinical practice. Upper respiratory tract infections (URTIs) are a common cause of olfactory loss. While most cases of olfactory loss due to URTIs are conductive and reversible, post-viral olfactory dysfunction (PVOD) persists despite symptom improvement.
View Article and Find Full Text PDFCombination of chronic inflammation and an altered tissue remodeling process are involved in the development of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). Studies demonstrated that mesenchymal stem cells expressing the progenitor gene were involved in a significant reduction of the chronic inflammatory process in the polypoid tissue. To evaluate the levels of CD133 (Prominin-1) in nasal polypoid tissue and its correlation with interleukin-8 (IL-8) and transforming growth factor β1 (TGF-β1).
View Article and Find Full Text PDFIntroduction: In May 2020, the World Health Organization recognized olfactory dysfunction as a COVID-19 symptom. The presence of hyposmia/anosmia may be a marker of good prognosis in COVID-19.
Objective: To associate the presence of olfaction disorder to the clinical condition severity in patients with COVID-19.
Introduction: Chronic rhinosinusitis (CRS) is termed difficult-to-treat when patients do not reach acceptable level of control despite adequate surgery, intranasal corticosteroid treatment and up to 2 short courses of systemic antibiotics or corticosteroids in the preceding year. Recently, high-volume corticosteroid nasal irrigations have been recommended for CRS treatment.
Objective: To assess high-volume budesonide nasal irrigations for difficult-to-treat CRS.
Unlabelled: Rhinosinusitis is one of the most common causes of fever of unknown origin in critically ill patients and should be systematically searched.
Objective: This study aims to evaluate the diagnostic and therapeutic effect of maxillary sinus puncture performed at the bedside in patients with infective rhinosinusitis hospitalized in an Intensive Care Unit of a high complexity care hospital.
Materials And Methods: This retrospective study looks into patients on mechanical ventilation with fever of unknown origin and signs of rhinosinusitis on CT images who were submitted to inferior meatus maxillary sinus puncture.
Unlabelled: Quality of life questionnaires have been increasingly used in clinical trials to help establish the impact of medical intervention or to assess the outcome of health care services. Among disease-specific outcome measures, SNOT-22 was considered the most suitable tool for assessing chronic rhinosinusitis and patients with nasal polyps.
Aims: To perform translation, cross-cultural adaptation and validation of the SNOT-22 to Brazilian Portuguese.
Braz J Otorhinolaryngol
November 2009
Unlabelled: The treatment of tympanic membrane perforations in the pediatric population with sequelae of chronic otitis media represents a challenge to otolaryngologists.
Aim: To assess the clinical and audiometric results of the inlay technique with a tragus cartilage plug.
Materials And Methods: We assessed 23 patients (ages between 1 and 15 years) who underwent plug tympanoplasty.
Unlabelled: Proper diagnosis of laryngeal benign lesions still brings doubts among experienced laryngologists, despite current diagnostic progress.
Aim: The goal of this study was to compare telelaryngoscopy (preoperative) with suspension laryngoscopy (intraoperative) on the diagnosis of vocal fold benign lesions.
Materials And Methods: We carried out a restrospective study analyzing 79 charts from patients followed up in a University Hospital.