Primigravida with Bernard-Soulier Syndrome: a case report.

Background: Bernard-Soulier Syndrome is a rare congenital bleeding disorder, mainly inherited in an autosomal recessive pattern. It is characterized by a genetic defect on one of the four genes encoding the subunits of the transmembrane protein complex GPIb-V-IX, physiologically expressed only in platelets. The exact phenotype varies widely from individual to individual depending on the particular mutation presented.

Oxidative stress and immunological alteration in women with preeclampsia.

Objectives: To determine plasma concentrations of malondialdehyde (MDA) and of inflammatory markers in women with preeclampsia.

Methods: A case-control study was conducted on 50 preeclamptic and 50 healthy pregnant women. The concentrations of MDA were determined by the method of thiobarbituric acid reactive substances.

Enzyme activity of superoxide dismutase and zincemia in women with preeclampsia.

Introduction: Preeclampsia is a complex syndrome of unknown aetiologic origin. It is characterized by the clinical triad of hypertension, edema and protenuria. Current concepts of the genesis of preeclampsia include endothelial dysfunction and oxidative stress.