Publications by authors named "Jose Antonio Ruiz Macia"

Article Synopsis
  • Condyloma acuminatum is usually caused by HPV and typically appears as pale, raised lesions, but some patients displayed pigmented lesions resembling seborrhoeic keratoses, which were confirmed to be HPV-positive.
  • In a retrospective study, 31 patients were analyzed for these unusual pigmented lesions, with most presenting as slow-growing and located at the base of the penis or pubis, primarily exhibiting the HPV-6 genotype.
  • The study concludes that these 'seborrhoeic keratosis-like' condylomas share clinical characteristics with seborrhoeic keratoses but are distinctly linked to HPV, with only a limited number of similar cases documented in existing literature.
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Article Synopsis
  • Strongyloidiasis is a parasitic disease common in Spain, particularly in the Mediterranean region, with a study analyzing clinical and epidemiological aspects in Vega Baja del Segura from 2009 to 2019.
  • Autochthonous cases (originating locally) were more prevalent among older males, especially those involved in agriculture, while imported cases primarily came from Latin America.
  • The research indicated that there’s no significant difference in treatment effectiveness or eosinophilia between autochthonous and imported cases, suggesting a need for systematic screening to identify and manage these infections more effectively.
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Neural lesions of the colon may be masses (schwannomas and neurofibromas) or, more frequently, small polyps including perineuromas, ganglioneuromas and granular cell tumors. Some neural lesions are associated with congenital syndromes (neurofibromatosis-1, multiple endocrine neoplasia-2B). Recently, a new entity has been described named mucosal Schwann cell hamartoma, consisting of an intramucosal neural proliferation; to date, less than forty cases have been reported.

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Introduction: The assessment of the state of immunosurveillance (the ability of the organism to prevent the development of neoplasias) in the blood has prognostic implications of interest in colorectal cancer. We evaluated and quantified a possible predictive character of the disease in a blood test using a mathematical interaction index of several blood parameters. The predictive capacity of the index to detect colorectal cancer was also assessed.

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Introduction: Strongyloides stercoralis infection is more prevalent in tropical regions but autochthonous cases have been reported in Spain, mainly in La Safor (Valencia). The objective is to describe the strongyloidiasis cases registered in a regional hospital of Alicante province (Spain) and to determine if they were autochthonous cases.

Methods: Retrospective study of all diagnosed cases of strongyloidiasis in Vega Baja Hospital (Orihuela, Alicante) between January 1999 and March 2016.

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Postirradiation pseudosclerodermatous panniculitis is a rare panniculitic disorder induced by radiotherapy. Clinically, it consists of an indurate plaque localized on the irradiated area that may appear months or even years after radiotherapy was administered. Histopathologically, postirradiation pseudosclerodermatous panniculitis is characterized by a mostly lobular panniculitis without vasculitis, with lipophagic granuloma involving the fat lobules, a variable inflammatory infiltrate of lymphocytes and plasma cells and sclerotic thickening of the connective tissue septa of the subcutis.

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Hepatoportal sclerosis (HPS) is characterized by presinusoidal intrahepatic portal hypertension associated with splenomegaly and anemia in patients with non-cirrhotic liver. Liver biopsy is essential, especially to rule out other processes. Being a disease of unknown etiology, the majority of cases have been described in eastern countries.

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Epithelioid-cell blue nevus is an unusual cytologic variant of blue nevus that has been recently described mostly in patients with Carney complex, although the lesion may also appear in patients with no evidence of Carney complex. This variant of blue nevus is composed of melanin laden large polygonal epithelioid melanocytes situated within the dermis. The neoplastic cells show no maturation with progressive descent and, in contrast with the usual stromal changes in blue nevi, epithelioid-cell blue nevus exhibits no dermal fibrosis.

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