Publications by authors named "Jose Antonio Lucas Castillo"
Allogeneic mesenchymal stem cell transplantation in healthy equine superficial digital flexor tendon: A study of the local inflammatory response.
Jaqueline Souza Brandão Marina Landim Alvarenga João Pedro Hubbe Pfeifer Vitor Hugo Dos Santos Carlos Eduardo Fonseca-Alves José Antonio Lucas Castillo
Res Vet Sci
June 2018
Article Synopsis
- The superficial digital flexor tendon (SDFT) in athletic horses is prone to injuries, and there are few treatment options available.
- This study investigates the local inflammatory response to allogeneic (from a donor) versus autologous (from the same animal) adipose tissue-derived mesenchymal stem cell (AT-MSC) transplantation in the equine tendon, using a control group for comparison.
- The results showed no significant differences in physical and morphological assessments across the groups, and the allogeneic AT-MSCs did not cause an adverse inflammatory response, indicating they behaved similarly to autologous transplants.