Publications by authors named "Jose Angel Berezo"
Article Synopsis
- Low levels of anti-SARS-CoV-2 S antibodies in critically ill COVID-19 patients are linked to higher mortality rates and suggest that these antibodies play a protective role.
- The study involved 92 ICU patients and showed that absence of these antibodies coincided with increased viral RNA in plasma and higher rates of N-antigenaemia.
- The findings indicate that monitoring antibody levels could be crucial for understanding patient outcomes and managing severe COVID-19 cases effectively.
Background: COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2 RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-19 is characterized by a dysregulated host response to this virus.
View Article and Find Full Text PDFBackground: Little is known on the participation of immunoglobulin isotypes and subclasses in the pathogenesis of the severe disease caused by the pandemic influenza virus (influenza A(H1N1)pdm09).
Objectives: (1) To evaluate the association between plasma levels of IgG1, IgG2, IgG3, IgG4, IgA, IgM, IgE and outcome in patients with severe pandemic influenza. (2) To evaluate the association between immunoglobulin and cytokine levels in these patients.
The development of new diagnostic methods based on molecular biology has led to evidence of the important role of respiratory viruses in chronic obstructive pulmonary disease (COPD) exacerbations. Cytokines and chemokines are recognized as key actors in the pathogenesis of COPD. The objective of this study was to evaluate the association between viral infection and host cytokine responses in 57 COPD patients hospitalized with an acute exacerbation.
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