Publications by authors named "Jose Alva"

Blood banks in developing countries have limited capability to typify common blood groups creating disparities in the access to blood units for patients with rare blood genotypes. We report the case of a Peruvian woman with metastatic breast cancer with KELnull phenotype (K), a rare blood group characterized by the lack of expression of all Kell antigens on the red blood cells (RBCs). The molecular studies identified that the patient's RBCs were homozygous for the nonsense c.

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The primary intestinal follicular lymphoma is a rare disease described in the last classification of lymphomas from WHO. It is a localized disease with excellent prognosis. We describe in this article ,a 64 year-old Peruvian female with abdominal pain and delayed vomiting for the last two years, has undergone a partial intestinal resection due to bowel obstruction.

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Article Synopsis
  • Follicular lymphoma (FL) is a common form of non-Hodgkin lymphoma mainly found in the U.S. and Europe, usually presenting with lymph node involvement rather than in a leukemic phase.
  • The study discusses seven patients diagnosed with leukemic FL and compares them to 24 cases from existing literature, revealing that patients with leukemic FL generally have a higher risk and worse prognosis.
  • The findings suggest variability in leukemic FL cases may be influenced by geographic differences, indicating that more extensive research is necessary to validate these results.
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We describe the clinical and pathological characteristics of seven patients who were human T-lymphotropic virus type 1 (HTLV-1) carriers and had a pathological diagnosis of de novo diffuse large B-cell lymphoma. Interestingly, three of our cases showed positive expression of Epstein-Barr-virus, (EBV-) encoded RNA within the tumor cells indicating a possible interaction between these two viruses. Furthermore, our three EBV-positive cases presented with similar clinical characteristics such as early clinical stage and low-risk indices.

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