Superconducting NbC nanoparticles synthesized by laser ablation in a liquid.

Niobium carbide (NbC) is a high-field type II superconductor with a critical temperature () of 11.1 K, slightly exceeding that of pure Nb ( = 9 K). The reduction of NbC to the nanoparticle scale leads to significant changes in its critical field and/or the superconducting temperature.

The alternative coproporphyrinogen III oxidase (CgoN) catalyzes the oxygen-independent conversion of coproporphyrinogen III into coproporphyrin III.

Nature utilizes three distinct pathways to synthesize the essential enzyme cofactor heme. The coproporphyrin III-dependent pathway, predominantly present in , employs an oxygen-dependent coproporphyrinogen III oxidase (CgoX) that converts coproporphyrinogen III into coproporphyrin III. In this study, we report the bioinformatic-based identification of a gene called , encoding a putative oxygen-independent counterpart, which we propose to term CgoN, from () .

Rashba Spin Splitting Limiting the Application of 2D Halide Perovskites for UV-Emitting Devices.

Layered lead halide perovskites have attracted much attention as promising materials for a new generation of optoelectronic devices. To make progress in applications, a full understanding of the basic properties is essential. Here, we study 2D-layered (BA)PbX by using different halide anions (X = I, Br, and Cl) along with quantum confinement.

Spatial and seasonal variability of picoplankton abundance and growth rates in the southern Bay of Biscay.

Autotrophic and heterotrophic picoplankton play fundamental roles in marine food webs and biogeochemical cycles. However, their growth responses have seldom been jointly assessed, including many temperate regions such as the Bay of Biscay. There, previous studies have shown their relevance in carbon fluxes.

Datasets describing optimization of the cutting regime in the turning of AISI 316L steel for biomedical purposes based on the NSGA-II and NSGA-III multi-criteria algorithms.

There are several methods of analysis used in the metalworking industry for dry machining processes and with Minimum Quantity Lubrication (MQL). Evolutionary methods [1] have been used in the decision-making process in the machining process to select the optimal data and to analyze the behavior of variables such as cutting speed (V), feed rate (f) and cutting depth (a). This work addresses the use of evolutionary algorithms of low dominance class II and III (NSGA-II and NSGA-III) to analyze from the multicriteria approach the initial wear of the cutting tool (VB), the energy consumption (E) and the machining time (t) in the turning process of the AISI 316L steel workpiece for biomedical purposes.

Calibration and Uncertainty Quantification for Single-Ended Raman-Based Distributed Temperature Sensing: Case Study in a 800 m Deep Coaxial Borehole Heat Exchanger.

Raman-based distributed temperature sensing (DTS) is a valuable tool for field testing and validating heat transfer models in borehole heat exchanger (BHE) and ground source heat pump (GSHP) applications. However, temperature uncertainty is rarely reported in the literature. In this paper, a new calibration method was proposed for single-ended DTS configurations, along with a method to remove fictitious temperature drifts due to ambient air variations.

Identifying sustainability priorities among value chain actors in artisanal common octopus fisheries.

Unlabelled: The United Nations (UN) Decade of Ocean Science highlights a need to improve the way in which scientific results effectively inform action and policies regarding the ocean. Our research contributes to achieving this goal by identifying practical actions, barriers, stakeholder contributions and resources required to increase the sustainability of activities carried out in the context of artisanal fisheries to meet UN Sustainable Development Goals (SDG) and International Year of Artisanal Fisheries and Aquaculture (IYAFA) Global Action Plan (GAP) Pillar targets. We conducted a novel 'social value chain analysis' via a participatory workshop to elicit perspectives of value chain actors and fisheries stakeholders associated with two Spanish artisanal common octopus () fisheries (western Asturias-Marine Stewardship Council [MSC] certified, and Galicia-non-MSC certified) about their priorities regarding sustainable octopus production and commercialization.

Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation.

is the only metazoan able to rejuvenate repeatedly after its medusae reproduce, hinting at biological immortality and challenging our understanding of aging. We present and compare whole-genome assemblies of and the nonimmortal using automatic and manual annotations, together with the transcriptome of life cycle reversal (LCR) process of We have identified variants and expansions of genes associated with replication, DNA repair, telomere maintenance, redox environment, stem cell population, and intercellular communication. Moreover, we have found silencing of polycomb repressive complex 2 targets and activation of pluripotency targets during LCR, which points to these transcription factors as pluripotency inducers in .

Analysis of the experience of the geriatric fracture program in two institutions in Colombia: a reproducible model?

Background: hip fracture is the major cause of morbidity and mortality. Geriatric fracture programs promise to improve the quality of care, health outcomes and reduce costs.

Objective: To describe the results related to the Geriatric fracture programs implementation in two Colombian institutions to assess reproducibility.

Increase in mercury and methylmercury levels with depth in a fish assemblage.

Despite their remoteness, deep-sea species bioaccumulate mercury, mostly in the form of the neurotoxin methylmercury (MeHg). Although the concentration of MeHg in the water column is known to increase with depth down to a maximum found at the base of the permanent thermocline, the knowledge of the relationship between MeHg content in marine species and their depth of occurrence is limited. We analyzed total mercury (THg) and MeHg concentrations in 25 species of fish inhabiting the Avilés Submarine Canyon and its adjacent shelf (Cantabrian Sea, North-East Atlantic) between 50 and 1868 m depth.

Long term prognostic benefit of complete revascularization in elderly presenting with NSTEMI: real world evidence.

The benefit of complete revascularization in elderly patients with non-ST elevation myocardial infarction (NSTEMI), and multivessel disease remains debated (MVD). The aim of our study was to determine the current long-term prognostic benefit of complete revascularization in this population. A retrospective cohort study of 1722 consecutive elderly NSTEMI patients was performed.

Evolution of perinatal outcomes and sociodemographic variables in Chile (1996-2017).

The evolution of birth weight (BW), birth length (BL), and gestational age at delivery (GAD) and their correlation with various maternal sociodemographic variables were studied in Chilean newborns from years 1996 to 2017. A slight decrease in the mean values of these perinatal outcomes was observed; however, their risk sub-categories increased significantly, especially for GAD, indicating an important deterioration. GAD was strongly correlated with BW and BL.

A Novel Stuttering Disfluency Classification System Based on Respiratory Biosignals.

Stuttering is the principal fluency disorder that affects 1% of the world population. Growing with this disorder can impact the quality of life of the adults who stutter (AWS). To manage this condition, it is necessary to measure and assess the stuttering severity before, during and after any therapeutic process.

Holothurian (Echinodermata) diversity and distribution in the central Cantabrian Sea and the Avilés Canyon System (Bay of Biscay).

Here we report on the holothurian fauna at the Avilés Canyon System (Natura 2000 Site of Community Importance), central Cantabrian Sea, northern Spain. The samples were collected during several cruises covering the shelf, the continental slope and the abyssal depth. We identified 174 specimens, belonging to 35 species of the seven orders of class Holothuroidea.

Social attributes can drive or deter the sustainability of bottom-up management systems.

Despite the growing popularity of bottom-up fishery management schemes not all socio-ecological systems respond well to this approach. Unfortunately, due to the heterogeneous nature of socio-ecological systems and lack of long-term, place-based studies we have yet to disentangle the impact of social attributes on their sustainability. The gooseneck barnacle fishery in Asturias, a fishery with a long-standing tradition of bottom-up management schemes and a plethora of spatially explicit data, provides a unique opportunity to test the effect of social attributes on 7, heterogeneous, co-managed, Territorial Use Rights for Fishing (TURFs) areas.

Development and external validation of a post-discharge bleeding risk score in patients with acute coronary syndrome: The BleeMACS score.

Background: Accurate 1-year bleeding risk estimation after hospital discharge for acute coronary syndrome (ACS) may help clinicians guide the type and duration of antithrombotic therapy. Currently there are no predictive models for this purpose. The aim of this study was to derive and validate a simple clinical tool for bedside risk estimation of 1-year post-discharge serious bleeding in ACS patients.

Large-scale ocean connectivity and planktonic body size.

Global patterns of planktonic diversity are mainly determined by the dispersal of propagules with ocean currents. However, the role that abundance and body size play in determining spatial patterns of diversity remains unclear. Here we analyse spatial community structure - β-diversity - for several planktonic and nektonic organisms from prokaryotes to small mesopelagic fishes collected during the Malaspina 2010 Expedition.

Paulomycin G, a New Natural Product with Cytotoxic Activity against Tumor Cell Lines Produced by Deep-Sea Sediment Derived Micromonospora matsumotoense M-412 from the Avilés Canyon in the Cantabrian Sea.

The present article describes a structurally novel natural product of the paulomycin family, designated as paulomycin G (), obtained from the marine strain M-412, isolated from Cantabrian Sea sediments collected at 2000 m depth during an oceanographic expedition to the submarine Avilés Canyon. Paulomycin G is structurally unique since-to our knowledge-it is the first member of the paulomycin family of antibiotics lacking the paulomycose moiety. It is also the smallest bioactive paulomycin reported.

Biomagnification of persistent organic pollutants in a deep-sea, temperate food web.

Polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs) and polychlorinated dibenzo-p-dioxins and -furans (PCDD/Fs) were measured in a temperate, deep-sea ecosystem, the Avilés submarine Canyon (AC; Cantabrian Sea, Southern Bay of Biscay). There was an increase of contaminant concentration with the trophic level of the organisms, as calculated from stable nitrogen isotope data (δN). Such biomagnification was only significant for the pelagic food web and its magnitude was highly dependent on the type of top predators included in the analysis.

Pharmacological Potential of Phylogenetically Diverse Actinobacteria Isolated from Deep-Sea Coral Ecosystems of the Submarine Avilés Canyon in the Cantabrian Sea.

Marine Actinobacteria are emerging as an unexplored source for natural product discovery. Eighty-seven deep-sea coral reef invertebrates were collected during an oceanographic expedition at the submarine Avilés Canyon (Asturias, Spain) in a range of 1500 to 4700 m depth. From these, 18 cultivable bioactive Actinobacteria were isolated, mainly from corals, phylum Cnidaria, and some specimens of phyla Echinodermata, Porifera, Annelida, Arthropoda, Mollusca and Sipuncula.

Atmospheric Dispersal of Bioactive Streptomyces albidoflavus Strains Among Terrestrial and Marine Environments.

Members of the Streptomyces albidoflavus clade, identified by 16S rRNA sequencing and phylogenetic analyses, are widespread among predominant terrestrial lichens (Flavoparmelia caperata and Xanthoria parietina) and diverse intertidal and subtidal marine macroalgae, brown red and green (Phylum Heterokontophyta, Rhodophyta, and Chlorophyta) from the Cantabrian Cornice. In addition to these terrestrial and coastal temperate habitats, similar strains were also found to colonize deep-sea ecosystems and were isolated mainly from gorgonian and solitary corals and other invertebrates (Phylum Cnidaria, Annelida, Echinodermata, Arthropoda, and Porifera) living up to 4700-m depth and at a temperature of 2-4 °C in the submarine Avilés Canyon. Similar strains have been also repeatedly isolated from atmospheric precipitations (rain drops, snow, and hailstone) collected in the same area throughout a year observation time.

Assessing the sustainability and adaptive capacity of the gooseneck barnacle co-management system in Asturias, N. Spain.

The gooseneck barnacle fishery in Asturias (N. Spain) has undergone three important changes: (1) the early implementation of a co-management system based on Territorial User Rights for Fishing, (2) a change in management measures (due to a decrease in landings), and (3) an economic crisis. This has allowed us to analyze the systems' sustainability in time through examining five critical variables: landings, effort, catch per unit effort (CPUE), mean market prices, and annual revenue.