T3 receptors in human pituitary tumors.

Objective: The purpose of this work was to investigate the synthesis of T3 receptors in human tumors of the anterior pituitary gland, its relationship with the hormone synthesized and/or secreted by the tumor and the post-surgical evolution of the patient.

Methods: Patients were evaluated clinically and by magnetic nuclear resonance to classify the adenoma according to their size. Hormonal concentrations in sera were determined by radioimmunoassay.

Antioxidants and methimazole in the treatment of Graves' disease: effect on urinary malondialdehyde levels.

Background: We have postulated that metabolic oxidation could be the source of signs and symptoms of hyperthyroidism. The present study was designed to evaluate urinary malondialdehyde levels in Graves' disease and compare this oxidative stress biomarker with the clinical evolution of patients suffering this illness.

Methods: We evaluated the concentration of urinary and serum malondialdehyde (MDA) in 36 patients with Graves' disease.