Publications by authors named "Jose A Alvarez-Castro"
Association between sociodemographic variables and delayed patient presentation among surgical neuro-oncology patients in Mexico City: a single institution experience.
J Neurooncol
January 2025
Article Synopsis
- Mexico has a high rate of nervous system cancer cases, and the study aimed to understand how sociodemographic factors influence the severity of clinical presentations in surgical neuro-oncology patients at a major hospital in Mexico City.
- The study involved analyzing medical records of 366 patients who underwent surgery in 2022, focusing on demographics like age, gender, marital status, and income levels, as well as their impact on clinical outcomes.
- Findings indicated that having more dependents and being divorced/separated were linked to worse clinical conditions, while being the primary provider and earning a higher monthly income were associated with better outcomes.
Article Synopsis
- Stereotactic Radiosurgery (SRS) is an effective treatment for patients with a limited number of small brain metastases, using either framed-based (FB) or mask-based (MB) fixation methods.
- A comparison of six studies with 509 patients found that while FB offers a slight advantage in local tumor control after one year, both FB and MB show similar outcomes in treatment time, radiation necrosis, and mortality rates.
- Further research is needed to confirm these findings and provide clearer guidance on the best fixation methods for SRS in brain metastasis treatment.
This research aims to propose a neurological surgery care protocol for the lesbian, gay, bisexual, transgender, queer, questioning, intersex, or asexual (LGBTQIA+) community. In recent years, people belonging to the LGBTQIA+ community have started to come out and express their identity due to growing awareness and various factors like the implementation of legal protections and rights in several countries; it is well documented in the literature that this community faces unique health needs as well as barriers and inequalities in healthcare. The lack of tailored training for medical specialists affects the level of quality and access to medical care for these individuals, and neurosurgical care is no exception.
View Article and Find Full Text PDFBackground: Sinonasal neuroendocrine carcinoma is a rare head and neck tumor that represents only 5% of sinonasal neoplasms. This lesion has a high risk of invasion to adjacent structures such as the orbit, skull base, and soft tissues, with symptoms usually being nonspecific. Most cases are diagnosed in late stages, decreasing overall survival without treatment.
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- The text discusses a unique case of acute necrotizing encephalopathy in a 26-year-old male who tested positive for SARS-CoV-2, highlighting the scarcity of this condition following COVID-19 infection.
- It outlines the typical MRI findings, such as symmetrical lesions primarily in the thalamus as well as the brainstem and cerebellum, along with accompanying edema.
- The article emphasizes the importance of close monitoring and the inclusion of specific MRI sequences in diagnostic protocols for accurate identification of this challenging condition.
Article Synopsis
- - Glioblastoma multiforme is a highly aggressive brain tumor, constituting around 60% of brain tumors in adults, often leading to poor survival rates, with multifocal lesions linked to worse outcomes.
- - A case study details a 43-year-old transgender woman who developed symptoms such as hemiplegia and seizures after long-term hormone therapy, leading to a diagnosis of wild-type glioblastoma confirmed through imaging and pathology.
- - The report suggests that prolonged use of steroid hormones may increase the risk of developing multifocal glioblastoma, highlighting the need for healthcare providers to consider neoplasms in transgender patients experiencing neurological symptoms, rather than attributing them solely to HIV-related conditions.
Gangliogliomas are central nervous system (CNS) tumors with a neuronal and glial component considered grade 1 according to the World Health Organization (WHO) classification. On the other hand, oligodendrogliomas are diffuse infiltrating gliomas (CNS WHO grade 2 or 3) characterized by both an isocitrate dehydrogenase mutation and 1p/19q co-deletion. There have been some cases with the coexistence of these two tumors.
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