Fatigue, depression, and physical activity in patients with malignant hyperthermia: a cross-sectional observational study.

Background: Malignant Hyperthermia (MH) is a pharmacogenetic disorder triggered by halogenated anesthesia agents/succinylcholine and characterized by hypermetabolism crisis during anesthesia, but also by day-to-day symptoms, such as exercise intolerance, that may alert the health professional.

Objective: The study aimed to analyze the incidence of fatigue in MH susceptible patients and the variables that can impact perception of fatigue, such as the level of routine physical activity and depression.

Methods: A cross-sectional observational study was carried out with three groups .